2024-07-25T10:50:57-05:00 2023-09-30 420714325 RSM US LLP 1001 WATER ST STE 500 TAMPA FL 33602 990 2022-10-01 521238026 AMERICAN INSTITUTE FOR CANCER RESEARCH AMER 2023287744 1560 WILSON BOULEVARD 425 ARLINGTON VA 22209 JOHN MCCALLA SECRETARY 2023287744 2024-07-25 1 JOHN MCCALLA 999009999 0 KRISTEN BARNETT P01234578 8133162300 2024-07-23 2 AAL1 IAL1 2022 2023-04-26 12:10:37Z X JOHN MCCALLA 1560 WILSON BOULEVARD 425 ARLINGTON VA 22209 13516566 0 X WWW.AICR.ORG X 1981 DC ADVANCES RESEARCH, EDUCATION AND COMMUNITY PROGRAMS FOR CANCER PREVENTION AND SURVIVORSHIP. 7 7 37 18254 0 0 12273935 10094745 1644130 1281556 350304 354155 205285 155338 14473654 11885794 1576143 1435966 0 0 3414235 3284102 647752 353328 2277832 8046039 7276731 13684169 12350127 789485 -464333 16915707 17918349 4780725 5675747 12134982 12242602 X AICR CHAMPIONS THE LATEST AND MOST AUTHORITATIVE SCIENTIFIC RESEARCH FROM AROUND THE WORLD ON CANCER PREVENTION AND SURVIVAL THROUGH DIET, WEIGHT AND PHYSICAL ACTIVITY, SO THAT WE CAN HELP PEOPLE MAKE INFORMED LIFESTYLE CHOICES TO REDUCE THEIR CANCER RISK. 0 0 5879581 386691 1208796 SEE SCHEDULE O. EDUCATIONEDUCATION PROGRAMSTHE AMERICAN INSTITUTE FOR CANCER RESEARCH (AICR) CHAMPIONS THE LATEST AND MOST AUTHORITATIVE SCIENTIFIC RESEARCH ON CANCER PREVENTION AND SURVIVAL THROUGH DIET, WEIGHT AND PHYSICAL ACTIVITY SO THAT WE CAN HELP PEOPLE MAKE INFORMED LIFESTYLE CHOICES TO REDUCE THEIR RISK. WE WANT TO LIVE IN A WORLD WHERE NO ONE DEVELOPS A PREVENTABLE CANCER. EDUCATION: AICR'S MESSAGEAICR'S EDUCATION PROGRAMS ARE EVIDENCE-BASED. THIS EVIDENCE COMES FROM BOTH THE RESEARCH WE FUND, AND THE CONCLUSIONS DRAWN IN OUR SCIENTIFIC REPORTS. FROM THESE FINDINGS WE PRODUCE EDUCATIONAL MATERIALS TO MEET A WIDE VARIETY OF NEEDS, ACROSS ALL STAGES OF THE CANCER CONTINUUM. AICR NEWSLETTERIN FISCAL YEAR (FY) 2023, AICR DISTRIBUTED MORE THAN 1.1 MILLION COPIES OF ITS NEWSLETTER TO SUPPORTERS. EACH QUARTERLY ISSUE IS FILLED WITH ARTICLES ON RESEARCH, PHYSICAL ACTIVITY, WEIGHT MANAGEMENT AND NUTRITION, INCLUDING RECIPES RELATED TO REDUCING CANCER RISK FOR PREVENTION AND HEALTHY SURVIVORSHIP. THE PRACTICAL TIPS, ADVICE AND FEATURED STORIES ARE ALL MADE POSSIBLE BY AICR'S GENEROUS SUPPORTERS. EACH ISSUE IS REVIEWED BY AN ADVISORY GROUP OF CLINICIANS, REGISTERED DIETITIANS, RECIPE DEVELOPERS AND CANCER RESEARCHERS. BROCHURES AND FACT SHEETSDEVELOPED TO PUT THE LATEST CANCER RESEARCH FINDINGS IN A CONCISE FORMAT, AICR'S BROCHURES, LEAFLETS AND FACT SHEETS OFFER MANY DIFFERENT AUDIENCES OUR EMPOWERING MESSAGE THAT WE CAN TAKE STEPS TO REDUCE OUR OWN CANCER RISK. FOLLOWING THE LAUNCH OF OUR THIRD EXPERT REPORT IN MAY 2018, ALL THESE RESOURCES WERE REVIEWED AND UPDATED TO REFLECT THE MOST CURRENT SCIENTIFIC EVIDENCE.IN FY23, WE OFFERED TWENTY DIFFERENT BROCHURE TITLES AND ELEVEN FACT SHEETS FOR CANCER PREVENTION AND CANCER SURVIVORSHIP. INDIVIDUALS CAN ORDER SINGLE FREE COPIES; HEALTH PROFESSIONALS AND MEDICAL CENTERS (E.G., HOSPITALS, CANCER CLINICS, ETC.) CAN MAKE BULK PURCHASES. AICR ALSO DISTRIBUTES BROCHURES AT CONFERENCES, EVENTS AND HEALTH FAIRS. IN FY23, AICR DISTRIBUTED OVER 33,000 BROCHURES AND OTHER PUBLICATIONS.HEALTH AIDSAICR PRODUCES HEALTH AIDS, INCLUDING INFOGRAPHICS, DOWNLOADABLES INFORMATION CARDS, MAGNETS AND MORE TO TURN LOWERING CANCER RISK INTO A "HANDS-ON" EXPERIENCE. INDIVIDUALS CAN ORDER SINGLE FREE COPIES; HEALTH PROFESSIONALS AND MEDICAL CENTERS (HOSPITALS, CANCER CLINICS, ETC.) CAN MAKE BULK PURCHASES. AICR ALSO DISTRIBUTES HEALTH AIDS AT CONFERENCES, EVENTS AND HEALTH FAIRS. IN FY23, AICR DISTRIBUTED MORE THAN 8,000 HEALTH AIDS.AICR WEBSITETHE GOAL OF THE AICR WEBSITE (WWW.AICR.ORG) IS TO INSPIRE USERS TO TAKE CONTROL OF THEIR HEALTH USING RESEARCH-BACKED CANCER PREVENTION AND SURVIVORSHIP RESOURCES. THE WEBSITE OFFERS UPDATED INFORMATION ON AICR RESEARCH; HEALTHY, CANCER-PROTECTIVE RECIPES AND FITNESS TIPS; AND A HOST OF INTERACTIVE TOOLS AND RESOURCES ON THE SCIENCE OF LOWERING CANCER RISK. IN FY23, AICR'S WEBSITE RECEIVED OVER 1.2 MILLION USERS (UNIQUE VISITORS) AND THE TOTAL NUMBER OF PAGE VIEWS EXCEEDED 2.1 MILLION.AICR'S WEBSITE ALSO INCLUDES INSPIRING STORIES OF IMPACT. THESE ARE TESTIMONIALS BY HEALTH PROFESSIONALS WHO REGULARLY USE AICR'S VARIOUS RESOURCES TO BUILD HEALTHIER COMMUNITIES THROUGH CANCER CENTERS, SURVIVORSHIP PROGRAMS AND MORE. ONE ONCOLOGY NUTRITIONIST AT THE DEMPSEY CENTER IN MAINE PROVIDES NUTRITION CONSULTATIONS TO PEOPLE WITH A CANCER DIAGNOSIS AND THEIR CARE PARTNERS; A REGISTERED DIETITIAN AT THE VCU MASSEY CANCER CENTER IN VIRGINIA USES AICR'S RESOURCES TO PROVIDE CANCER PATIENTS AND SURVIVORS WITH INFORMATION ABOUT WHAT TO EAT AND WHY WE EAT FOR WELLNESS. AND YET ANOTHER REGISTERED DIETITIAN AT PENN MEDICINE'S ABRAMSON CANCER CENTER IN PENNSYLVANIA HELPS CANCER PATIENTS NAVIGATE THE RELATIONSHIP BETWEEN NUTRITION, TREATMENT AND POST-TREATMENT QUALITY OF LIFE.THERE ARE ALSO TESTIMONIALS BY PEOPLE WHO HAVE BEEN DIRECTLY AFFECTED BY CANCER OR KNOW SOMEONE WHO HAS BEEN AFFECTED BY CANCER, AND HOW THEY HAVE USED AICR'S RESOURCES TO HELP THEMSELVES OR OTHERS NAVIGATE CANCER FROM DIAGNOSIS THROUGH SURVIVORSHIP. ONE INSPIRING STORY IS FROM A BREAST CANCER SURVIVOR WHO WAS DIAGNOSED WHILE PREGNANT. AFTER SURGERY, CHEMO, RADIATION AND DELIVERING A HEALTHY BABY, SHE JOINED TEAM AICR AND RAN THE LONDON MARATHON TO RAISE AWARENESS OF AICR'S MESSAGE ABOUT THE IMPORTANCE OF PHYSICAL ACTIVITY AND TO RAISE FUNDS IN SUPPORT OF CANCER RESEARCH AT AICR.E-PUBLICATIONAICR'S MONTHLY NEWSLETTER, CANCER FOCUS, ENCOMPASSES THREE AREAS: HOW TO START LIVING FOR LOWER CANCER RISK TODAY; BREAKING NEWS AND CURRENT RESEARCH IN THE FIGHT AGAINST CANCER; AND RESEARCH, RECIPES AND FOODS THAT HELP SURVIVORS NAVIGATE THEIR CANCER JOURNEY. AS OF SEPTEMBER 2023, OVER 300,000 PEOPLE HAVE RECEIVED CANCER FOCUS.AICR BLOG AND SOCIAL MEDIATHE AICR BLOG (AICR.ORG/RESOURCES/BLOG) SPEAKS TO SUPPORTERS; CANCER PATIENTS, SURVIVORS AND CAREGIVERS; HEALTH PROFESSIONALS; THE MEDIA AND THE GENERAL PUBLIC. THE AICR BLOG IS ONE WAY AICR ENGAGES IN AN ONGOING DISCUSSION ABOUT RESEARCH AND SEPARATES CANCER MYTHS FROM CANCER FACTS, ESPECIALLY THOSE THAT ARE HOT TOPICS IN THE MEDIA. IT IS WHERE WE SHARE OUR TAKE ON CURRENT NEWS AND ENCOURAGE READERS TO POST COMMENTS. IN FY23, THE AICR BLOG RECEIVED OVER 451,000 USERS (UNIQUE VISITORS), AND NEARLY 548,000 PAGE VIEWS. FACEBOOK AND TWITTER HAVE HISTORICALLY BEEN IMPORTANT COMMUNICATION CHANNELS FOR AICR TO SHARE MESSAGES WITH A WIDE AND DIVERSE AUDIENCE. IN ADDITION TO FACEBOOK AND TWITTER, AICR INCREASED SOCIAL MEDIA EFFORTS IN FY23 TO HELP GROW OUR BRAND ON INSTAGRAM, LINKEDIN, PINTEREST AND YOUTUBE. AT THE END OF FY23, AICR HAD A TOTAL OF 60,601 SOCIAL MEDIA FOLLOWERS FOR 15.1% GROWTH COMPARED TO FY22. OVER THE COURSE OF FY23 AICR SOCIAL MEDIA CHANNELS HAD A TOTAL OF 1,523,976 IMPRESSIONS AND 74,544 ENGAGEMENTS, 21.8% MORE ENGAGEMENTS OVER FY22.LINKEDIN SAW THE LARGEST GROWTH IN FY23 WITH 4,885 NEW FOLLOWERS, TOTALING 14,151 FOLLOWERS AT THE END OF SEPTEMBER 2023. THIS IS A 52.7% INCREASE COMPARED TO FY22. AT THE CLOSE OF FY23, AICR'S FACEBOOK PAGE HAD 28,257 FOLLOWERS AND ON AVERAGE, OUR CONTENT REACHED OVER 4,000 USERS DAILY. TWITTER (@AICRTWEETS) HAD 7,882 FOLLOWERS AND LINKEDIN HAD 14,151.CANCER PREVENTION MONTHFEBRUARY IS CANCER PREVENTION MONTH TO RAISE AWARENESS THAT 40% OF CANCERS CAN BE PREVENTED AND PROVIDE EMPOWERING MESSAGES TO HELP CANCER SURVIVORS TAKE CONTROL OF THEIR HEALTH.WE ENCOURAGED PEOPLE TO "TAKE THE TEN" AN ONLINE TOOL (AICR'S HEALTHY10 CHALLENGE) TO HELP PEOPLE CHANGE THEIR LIFESTYLE HABITS AND PUT AICR'S CANCER PREVENTION RECOMMENDATIONS INTO ACTION. THE HEALTHY10 CHALLENGE IS A FREE, 10-WEEK INTERACTIVE PROGRAM DESIGNED TO HELP INDIVIDUALS IMPROVE THEIR DIET, NUTRITION, PHYSICAL ACTIVITY AND WEIGHT FOR LOWER CANCER RISK AND BETTER OVERALL HEALTH. AT THE END OF SEPTEMBER 2023, ALMOST 8,000 INDIVIDUALS HAD SIGNED UP FOR THE CHALLENGE. IN FEBRUARY 2023, AICR'S WEBSITE HAD OVER 99,061 USERS, 220 PEOPLE TOOK THE CANCER HEALTH CHECK AND AICR ACQUIRED OVER 500 NEW EMAIL ADDRESSES. AICR'S SOCIAL MEDIA PLATFORMS GAINED 458 NEW FOLLOWERS, EARNED OVER 108,508 IMPRESSIONS AND RECEIVED OVER 4,700 ENGAGEMENTS.HEALTHY10 CHALLENGEAICR'S EVIDENCE-BASED MATERIALS HELP PEOPLE LEARN ABOUT WHAT THEY CAN DO TO PROTECT THEMSELVES FROM CANCER, BUT WE ALSO SUPPLY THEM WITH TOOLS THAT SUPPORT THE KIND OF REAL, LASTING BEHAVIOR CHANGE THAT LEADS TO LOWER RISK. THE HEALTHY10 CHALLENGE IS A 10-WEEK, FREE, INTERACTIVE, ONLINE PROGRAM TO HELP USERS IMPROVE THEIR DIET, NUTRITION, PHYSICAL ACTIVITY AND WEIGHT FOR LOWER CANCER RISK AND BETTER OVERALL HEALTH. IT IS BASED ON AICR'S EVIDENCE-BASED CANCER PREVENTION RECOMMENDATIONS AND IS INTENDED FOR ADULTS WANTING TO REDUCE THEIR CANCER RISK (INCLUDING RECURRENCE AND SECONDARY CANCER). ITS MOTIVATIONAL CHALLENGES ALTERNATE BETWEEN DIET AND PHYSICAL ACTIVITY TO HELP USERS EAT SMARTER AND MOVE MORE. EACH WEEK USERS WILL BE GIVEN A GOAL AS WELL AS TIPS AND TOOLS TO HELP CONQUER EACH CHALLENGE. THIS IS A SIMPLE AND FUN WAY TO BECOME HEALTHIER AND TAKE ACTION TO REDUCE CANCER RISK AT ANY STAGE OF LIFE AND MEETS INDIVIDUALS WHERE THEY ARE AT IN THEIR HEALTH JOURNEY. THERE WAS A TOTAL OF OVER 7,803 EMAILS COLLECTED AND INDIVIDUALS WHO SIGNED UP FOR THE HEALTHY10 CHALLENGE IN FY23. 2144249 1049275 72760 SEE SCHEDULE O.RESEARCHAICR RESEARCH PROGRAMSSCIENTIFIC STUDY OF THE RELATIONSHIP OF DIET, PHYSICAL ACTIVITY AND WEIGHT MANAGEMENT TO CANCER RISK AND SURVIVORSHIP CONTINUES TO BE THE PRIMARY FOCUS OF AMERICAN INSTITUTE FOR CANCER RESEARCH (AICR) RESEARCH INVESTMENT AND ACTIVITIES. EVIDENCE SHOWS THAT WEIGHT MANAGEMENT, PHYSICAL ACTIVITY, FOOD AND NUTRITION PLAY IMPORTANT ROLES IN CANCER PREVENTION, TREATMENT AND SURVIVORSHIP. RESEARCH SHOWS THAT APPROXIMATELY 40% OF ALL CANCERS COULD BE PREVENTED IF EVERYONE REACHED AND MAINTAINED A HEALTHY WEIGHT, FOLLOWED THE RECOMMENDATIONS FOR REGULAR PHYSICAL ACTIVITY, CONSUMED A HEALTHY DIET, AVOIDED USE OF TOBACCO PRODUCTS AND FOLLOWED APPROPRIATE SCREENING AND VACCINATION GUIDELINES. AICR IS UNIQUE IN ITS FOCUS ON PREVENTING CANCER AND IMPROVING SURVIVAL THROUGH DIET, NUTRITION, BODY COMPOSITION AND PHYSICAL ACTIVITY. WE COLLATE AND INTERPRET THE LATEST AND MOST AUTHORITATIVE GLOBAL SCIENTIFIC RESEARCH ON THE LINKS BETWEEN CANCER AND DIET, NUTRITION, BODY COMPOSITION AND PHYSICAL ACTIVITY. WE THEN TRANSLATE OUR FINDINGS INTO PRACTICAL, CLEAR, EVIDENCE-BASED RECOMMENDATIONS ON CANCER PREVENTION FOR USE BY HEALTH PROFESSIONALS, INDIVIDUALS AND GOVERNMENTS WORLDWIDE.IN TOTAL, THROUGH FY23, AICR HAS COMMITTED MORE THAN $111 MILLION FOR HUNDREDS OF INDIVIDUAL RESEARCH PROJECTS AT UNIVERSITIES, HOSPITALS AND RESEARCH CENTERS. AICR PIONEERED THE FUNDING OF RESEARCH EXAMINING DIET AND CANCER AND WAS THE FIRST ORGANIZATION TO DEVOTE ITSELF TO STUDYING THE ROLE OF DIET AND OTHER LIFESTYLE FACTORS IN LOWERING CANCER RISK. THE RESEARCH THAT WE HAVE FUNDED HAS HELPED TRANSFORM THE ONCE-RADICAL NOTION THAT EVERYDAY CHOICES CAN DRAMATICALLY REDUCE CANCER RISK INTO A UNIVERSALLY ACCEPTED MEDICAL FACT AND PUBLIC HEALTH POLICY.OUR MULTI-FACETED INVESTMENT IN RESEARCH CONTINUES ACROSS SEVERAL CORE ACTIVITIES.AICR GRANT PROGRAMSTHE AICR GRANT PROGRAMS ARE DEDICATED TO FUNDING RESEARCH ON CANCER PREVENTION, TREATMENT AND SURVIVAL RELATED TO DIET, NUTRITION, BODY COMPOSITION AND PHYSICAL ACTIVITY. ALL APPLICATIONS ARE SUBJECTED TO RIGOROUS PEER REVIEW.INSPIRE RESEARCH CHALLENGE: IN 2023, AICR INITIATED A NEW GRANT PROGRAM, THE "INSPIRE RESEARCH CHALLENGE," IN ADDITION TO OUR EXISTING INVESTIGATOR-INITIATED RESEARCH GRANT PROGRAM. THE INSPIRE RESEARCH CHALLENGE IS A PARTNERSHIP WITH THE WORLD CANCER RESEARCH FUND (WCRF) INTERNATIONAL WITH THE GOAL OF SUPPORTING INNOVATIVE IDEAS FROM EARLY CAREER RESEARCHERS WITHIN 2-6 YEARS OF PHD COMPLETION. IN FEBRUARY 2023, AICR AND WCRF HOSTED AN INFORMATION WEBINAR TO LAUNCH THE INSPIRE RESEARCH CHALLENGE, TO STIMULATE INTEREST FROM POTENTIAL APPLICANTS AND PROVIDE GUIDANCE REGARDING THE SCOPE AND APPLICATION PROCESS. OVER 200 RESEARCHERS ATTENDED. FOR THE FIRST CYCLE OF THE INSPIRE RESEARCH CHALLENGE, WE RECEIVED 48 LETTERS OF INTENT, INVITED 14 FULL APPLICATIONS AND FUNDED 6 GRANTS THROUGH COLLABORATION WITH WCRF INTERNATIONAL. THE INSPIRE RESEARCH CHALLENGE GRANT REVIEW PANEL WAS CHAIRED BY DR. RICHARD SIMPSON (UNIVERSITY OF ARIZONA) AND DR. AMANDA CROSS (IMPERIAL COLLEGE LONDON) WITH WRITTEN REVIEW REPORTS PROVIDED FROM EXTERNAL INDEPENDENT CONTENT EXPERTS.INVESTIGATOR-INITIATED RESEARCH GRANT (IIG) PROGRAM: FOR THE 2023 CYCLE OF THE INVESTIGATOR-INITIATED RESEARCH GRANT PROGRAM GRANT CYCLE, WE RECEIVED 122 LETTERS OF INTENT: 53 ON CANCER PREVENTION, 52 ON CANCER SURVIVORSHIP AND 17 COVERING BOTH AREAS. WE INVITED 48 APPLICANTS TO SUBMIT FULL APPLICATIONS AND RECEIVED 45 FOR OUR GRANT PANEL TO REVIEW AND DISCUSS.FOR THE 2023 GRANT CYCLE, WE WELCOMED CO-CHAIRS DR. LINDA COOK (CANCER CENTER ASSOCIATE DIRECTOR FOR POPULATION SCIENCE, TENURED PROFESSOR IN THE DEPARTMENT OF EPIDEMIOLOGY, COLORADO SCHOOL OF PUBLIC HEALTH) AND DR. ERIK NELSON (ASSOCIATE PROFESSOR OF MOLECULAR AND INTEGRATIVE PHYSIOLOGY, UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN). THE GRANT REVIEW PANEL INCLUDED 14 ADDITIONAL EXPERTS WITH THE DEPTH AND BREADTH OF EXPERTISE TO EVALUATE THE SCIENTIFIC MERIT AND IMPACT OF THE PROPOSED RESEARCH. THE GRANT REVIEW PANEL MEETING WAS CONDUCTED IN A HYBRID FORMAT WITH THE TWO CO-CHAIRS JOINING US IN-PERSON AND THE OTHER REVIEWERS ATTENDING BY VIDEO CONFERENCE.REVIEWERS- DORATHA BYRD, PHD, MPH, MOFFITT CANCER CENTER- ILONA CSIZMADI, PHD, UNIVERSITY OF CALGARY- MICHAEL DE LISIO, PHD, UNIVERSITY OF OTTAWA- CHRISTINA DIELI-CONWRIGHT, PHD, MPH, DANA-FARBER CANCER INSTITUTE- EMILY LAVOY, PHD, UNIVERSITY OF HOUSTON- YUE LIAO, PHD, MPH, CPH, UNIVERSITY OF TEXAS, ARLINGTON- LYDIA LYNCH, PHD, HARVARD UNIVERSITY- GERARDO MACKENZIE, PHD, UNIVERSITY OF CALIFORNIA, DAVIS- CONNIE ROGERS, PHD, PENNSYLVANIA STATE UNIVERSITY- PAUL SPAGNUOLO, PHD, UNIVERSITY OF GUELPH- ERIN VAN BLARIGAN, SCD, UNIVERSITY OF CALIFORNIA, SAN FRANCISCO- ELIZABETH WELLBERG, PHD, THE UNIVERSITY OF OKLAHOMA HEALTH SCIENCES- PATRICIA WOLF, PHD, RDN, PURDUE UNIVERSITY- SUZANNA ZICK, MPH, ND, UNIVERSITY OF MICHIGANFUNDED GRANTSIIG1. IMPACT OF AEROBIC EXERCISE ON ADIPOSE, MUSCLE AND SARCOPENIA IN PEOPLE WITH COLON CANCER. KRISTIN CAMPBELL, PHD, UNIVERSITY OF BRITISH COLUMBIA, VANCOUVER, CANADA 2. FOOD FOR THOUGHT: PILOT STUDY OF A MIND DIET INTERVENTION IN TRIPLE NEGATIVE BREAST CANCER SURVIVORS. TONYA ORCHARD, PHD, RD, THE OHIO STATE UNIVERSITY, COLUMBUS, OH3. DIETARY SELENIUM-DEPENDENT MODULATION OF PD-L1 IN ACUTE MYELOID LEUKEMIA INITIATING STEM CELLS. K. SANDEEP PRABHU, PHD, THE PENNSYLVANIA STATE UNIVERSITY, STATE COLLEGE, PA4. INTEGRATION OF IMMUNOLOGY AND MICROBIOLOGY INTO EPIDEMIOLOGIC RESEARCH ON EARLY-ONSET COLORECTAL CANCER FOR PRECISION ONCOLOGY. TOMOTAKA UGAI, MD, PHD, BRIGHAM AND WOMEN'S HOSPITAL, BOSTON, MA INSPIRE (FUNDED BY THE WCRF/AICR NETWORK)5. EARLY LIFE INFECTIONS: PATHWAYS TO PREVENT ADULT CANCERS? JULIE AARESTRUP, MS, PHD, BISPEBJERG AND FREDERIKSBERG HOSPITAL, KBENHAVN, DENMARK6. IMPACT OF SLEEP ON THE DEVELOPMENT OF REPRODUCTIVE SYSTEM CANCERS. CHRISTOS CHALITSIOS, PHD, MSC, UNIVERSITY OF IOANNINA, IOANNINA, GREECE7. LIFE-S-CAN: CLINICAL TOOL TO SCREEN AND IMPROVE CANCER SURVIVORSHIP CARE AND QUALITY OF LIFE. ALICE CHAPLIN, PHD, MSC, CONSORCIO CENTRO DE INVESTIGACIN BIOMDICA EN RED, MADRID, SPAIN8. EXPLORING THE MECHANISMS LINKING SLEEP PATTERNS AND BREAST CANCER RISK. SHAN LUO, PHD, MPH, UNIVERSITY OF HONG KONG, POK FU LAM, HONG KONG9. HOW HIGH-INTENSITY EXERCISE AND FIBER AFFECT IMMUNOTHERAPY OUTCOMES FOR PATIENTS WITH MELANOMA. DONG-WOO KANG, PHD, CEP/CET, DANA-FARBER CANCER INSTITUTE, BOSTON, MA10. USING AI CHATBOTS TO SUPPORT FAMILIES OF CHILDREN WITH CANCER. MICAH SKEENS, PHD, APRN, FAAN, RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL, COLUMBUS, OHAICR EXPERT REPORTSSINCE 2007, AICR AND ITS INTERNATIONAL AFFILIATE, THE WORLD CANCER RESEARCH FUND (WCRF), HAVE WORKED TOGETHER ON THE CONTINUOUS UPDATE PROJECT (CUP). THE CUP HAS BUILT ON THE SYSTEMATIC LITERATURE REVIEW CONDUCTED FOR OUR 2007 SECOND EXPERT REPORT FOOD, NUTRITION, PHYSICAL ACTIVITY, AND THE PREVENTION OF CANCER: A GLOBAL PERSPECTIVE. IN 2018, AICR AND WCRF PUBLISHED DIET, NUTRITION, PHYSICAL ACTIVITY AND CANCER: A GLOBAL PERSPECTIVE, THE THIRD EXPERT REPORT TO UPDATE BOTH THE ASSESSMENT OF THE EVIDENCE FOR THE IMPACT OF EACH FACTOR ON CANCER RISK AND REVISE THE CANCER PREVENTION RECOMMENDATIONS THE CUP PROVIDES THROUGH TIMELY REVIEWS AND EXPERT PANEL ASSESSMENTS OF THE AVAILABLE PEER-REVIEWED EVIDENCE. THE CUP REPORTS HAVE IDENTIFIED EMERGING RESEARCH AREAS AND KNOWLEDGE GAPS THAT COULD BE ADDRESSED WITHIN OUR GRANT PROGRAM. EQUALLY, NEW DATA GENERATED FROM STUDIES FUNDED THROUGH OUR GRANT PROGRAM ARE INCLUDED IN THE CUP REVIEWS. THUS, AICR'S RESEARCH GRANT PROGRAMS AND THE CUP ACT SYNERGISTICALLY TO STRENGTHEN THE SCIENTIFIC EVIDENCE ON THE IMPACT OF DIET, NUTRITION, BODY COMPOSITION AND PHYSICAL ACTIVITY ON CANCER PREVENTION AND CONTROL.IN 2020, THE CUP EMBARKED ON A PROCESS OF EVALUATION AND STRATEGIC PLANNING, TERMED THE CUP TRANSITION, WITH A PANEL OF INTERNATIONAL EXPERTS TO DETERMINE THE OPTIMAL DIRECTIONS FOR FUTURE RESEARCH IN THIS FIELD. THIS PROCESS CONTINUED THROUGH 2021, CONCLUDING WITH THE DEVELOPMENT OF A NEW STRATEGY THAT WAS OPERATIONALIZED IN 2022. CONCURRENTLY, THE CUP TRANSITION PANEL REVIEWED THE COMPLETED SYSTEMATIC LITERATURE REVIEWS ON MEDICAL OUTCOMES AND QUALITY OF LIFE IN BREAST CANCER SURVIVORS AND SUBMITTED SEVERAL MANUSCRIPTS FOR PUBLICATION IN PEER-REVIEWED JOURNALS. 8023830 1 1 0 0 0 0 0 0 0 1 1 0 1 1 1 1 1 0 0 0 1 1 0 1 0 0 0 1 0 1 0 0 0 0 0 0 0 1 0 0 0 0 0 1 1 1 0 0 1 X 51 0 1 37 1 0 1 UK NL HK FR 0 0 0 0 0 0 0 0 0 0 X 7 7 0 0 0 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 1 0 AL AR CA FL GA HI IL IN KS KY MD MA MI MN MS NH NJ NM NY NC OR PA RI SC TN UT VA WV WI X X JENNIFER MERCER 2023287744 1560 WILSON BOULEVARD 425 ARLINGTON VA 22209 MELVIN HUTSON BOARD CHAIR 2.00 X 0 0 0 SUSAN PEPPER BOARD SECRETARY-TREASURER 2.00 X X 0 0 0 JEFFREY BUNN BOARD MEMBER (THRU 08/03/23) 2.00 X 0 0 0 GEOFFREY HERALD BOARD MEMBER 2.00 X 0 0 0 FRANK HILL BOARD MEMBER 2.00 X 0 0 0 MARILYN GENTRY BOARD MEMBER 2.00 X 0 0 0 JOHN MCCALLA BOARD MEMBER 2.00 X 0 0 0 JOSEPH SWARTZ BOARD MEMBER 2.00 X 0 0 0 DEIRDRE MCGINLEY-GIESER EXECUTIVE VP 40.00 X 176220 0 17733 MARILYN GENTRY PRESIDENT, WCRF INT'L & AICR 3.00 15.00 X 0 101236 0 JENNIFER MERCER SENIOR VP DEVELOPMENT 40.00 X 174996 0 18434 MICHAEL MCCARN CHIEF INFORMATION OFFICER 40.00 X 145848 0 23351 NIGEL BROCKTON VP RESEARCH 40.00 X 148831 0 20966 PATRICIA BODENSTEDT VP FINANCE 40.00 X 151512 0 15390 PETER CROWLEY MCCARTY VP, CORP FOUNDATIONS (THRU 03/15/23) 40.00 X 130301 0 552 927708 101236 96426 12 0 1 0 SOUTHWEST PUBLISHING & MAILING CORP 4000 SE ADAMS STREET TOPEKA KS 66609 MAILHOUSE CONSULTANT 1604869 THE DATA CENTER INC 9720 CAPITAL COURT SUITE 101 MANASSAS VA 20110 DATA PROCESSING FEES 571785 RMI DIRECT MARKETING INC 44 OLD RIDGEBURY RD PLAZA ONE DANBURY CT 06810 LIST RENTAL CONSULTANT 429020 CHLORINE LLC 1627 K STREET NE SUITE 710 WASHINGTON DC 20006 REAL ESTATE MANAGEMENT 416521 DIRECT RESPONSE CONSULTING SERVICES 7918 JONES BRANCH DRIVE MCLEAN VA 22102 FUNDRAISING CONSULTANT 407244 8 10094745 10094745 BROCHURE SALES 900099 1208796 1208796 SERVICE FEES 900099 72760 72760 1281556 269952 269952 1714975 1630772 84203 84203 84203 MAILING LIST RENTAL 900099 126566 126566 OTHER INCOME 900099 28772 28772 155338 11885794 1281556 0 509493 577500 577500 858466 858466 193953 193953 2586734 1205826 1005998 374910 44997 11267 24443 9287 260892 134124 89661 37107 197526 107656 63564 26306 14818 8982 2735 3101 120080 72790 22160 25130 353328 353328 32478 32478 695561 533229 162332 1189 957 232 218070 147358 40264 30448 313580 149849 135177 28554 311746 177695 93524 40527 235895 177647 57081 1167 7964 7964 40640 40640 60878 60878 60341 34394 18103 7844 23889 13616 7167 3106 POSTAGE & DELIVERY 1886719 1272470 33110 581139 PRINTING & PUBLICATION 1646228 1187981 59743 398504 DATA PROCESSING 742602 424836 110183 207583 MAILHOUSE FEES 357403 345496 4948 6959 506650 319853 44197 142600 12350127 8023830 2048465 2277832 X 3985648 2488151 5446 1492051 9899 10934 5948992 4248954 1860511 2116604 97957 76389 613345 274121 1115564 864995 310910 250569 1305239 1416722 5522828 7205618 1246026 2318438 16915707 17918349 476349 600621 2179249 1856246 2125127 3218880 4780725 5675747 X 5674642 4316897 6460340 7925705 12134982 12242602 16915707 17918349 X -464333 498931 73022 X X 0 1 X 1 0 X 16279595 12226058 10837807 12273935 10094745 61712140 16279595 12226058 10837807 12273935 10094745 61712140 5341050 56371090 489512 240918 208468 275814 237474 1452186 46605 253743 1555351 203990 155338 2215027 65379353 6464020 0.86220 0.86610 X SCHEDULE A, PART II, LINE 10, EXPLANATION OF OTHER INCOME: OTHER INCOME - 2018 AMOUNT: $ 46,605. 2019 AMOUNT: $ 253,743. 2020 AMOUNT: $ 1,555,351. 2021 AMOUNT: $ 203,990. 2022 AMOUNT: $ 155,338. RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 2084888 18145 261636 0 174330 0 2190339 2504791 290307 -537422 172788 2084888 2045005 297100 367867 205181 2504791 2123034 3365 242611 324005 2045005 1911046 292469 92303 172784 2123034 0.16000 0.30000 0.54000 0 0 5900 5900 513031 281589 231442 350475 346811 3664 246158 236595 9563 250569 CHARITABLE GIFT ANNUITIES 2618639 F CHARITABLE REMAINDER UNITRUSTS 789324 F CANCER RESEARCH FUND 3797655 F 7205618 BENEFICIAL INT. IN PERPETUAL TRUST 322275 DUE FROM AFFILIATES 665383 RIGHT OF USE ASSETS 1330780 2318438 LIABILITY CHARITABLE GIFT ANNUITIES 744787 LIABILITY CHARITABLE REMAINDER 347640 RIGHT OF USE LIABILITIES 2126453 3218880 X 12425269 498931 73022 571953 11853316 32478 32478 11885794 12317649 0 12317649 32478 32478 12350127 PART V, LINE 4: THE ORGANIZATION'S ENDOWMENT FUNDS ARE ESTABLISHED TO FURTHER THE MISSION OF THE AMERICAN INSTITUTE FOR CANCER RESEARCH. THE PERSON ESTABLISHING THE FUND DESIGNATED THE PURPOSE OF THEIR FUND, (I.E., CANCER RESEARCH, EDUCATION OR GENERAL OPERATING). PART X, LINE 2: THE INSTITUTE IS RECOGNIZED AS EXEMPT FROM FEDERAL INCOME TAX UNDER SECTION 501(C)(3) OF THE INTERNAL REVENUE CODE ON INCOME OTHER THAN UNRELATED BUSINESS INCOME. NO PROVISION FOR INCOME TAXES IS REQUIRED AS OF SEPTEMBER 30, 2023 AND 2022, SINCE THE INSTITUTE HAD NO UNRELATED BUSINESS INCOME. THE INSTITUTE HAS BEEN RECOGNIZED BY THE INTERNAL REVENUE SERVICE AS A PUBLICLY SUPPORTED ORGANIZATION AND IS THEREFORE NOT A PRIVATE FOUNDATION. MANAGEMENT ANNUALLY REVIEWS ITS TAX POSITION AND HAS DETERMINED THAT THERE ARE NO UNCERTAIN TAX POSITIONS THAT REQUIRE RECOGNITION IN THE FINANCIAL STATEMENTS. PART XI, LINE 2D - OTHER ADJUSTMENTS: CHANGE IN VALUE OF SPLIT INTEREST AGREEMENT LIABILITY 69,342. NET GAIN ON INTEREST IN PERPETUAL TRUST 3,680. 1 EUROPE (INCLUDING ICELAND & GREENLAND) 0 0 GRANTMAKING 693466 NORTH AMERICA 0 0 GRANTMAKING 165000 0 0 0 0 0 0 858466 0 858466 EUROPE (INCLUDING ICELAND & GREENLAND) - ALBANIA, ANDORRA, AUSTRIA, BELGIUM RESEARCH 693466 WIRE 0 NORTH AMERICA - CANADA AND MEXICO, BUT NOT THE UNITED STATES EDUCATION 165000 CASH/CHECK 0 2 0 0 0 1 0 0 0 PART I, LINE 2: AT THE END OF THE FIRST YEAR OF ANY TWO-YEAR GRANT, THE PRINCIPAL INVESTIGATOR MUST SUBMIT A PROGRESS REPORT, INCLUDING ABSTRACTS AND PUBLICATIONS OF RESEARCH SUPPORTED IN WHOLE OR IN PART BY AICR. AT THE DISCRETION OF AICR, FUNDS FOR THE SECOND YEAR OF THE GRANT MAY BE WITHHELD BASED ON THE PROGRESS REPORT OR IF PROGRESS REPORTS ARE NOT SUBMITTED. FINAL SCIENTIFIC REPORT: WITHIN THREE MONTHS OF THE COMPLETION OF THE GRANT PERIOD, AICR REQUIRES A FINAL COMPREHENSIVE REPORT TO OUTLINE THE PROJECT'S ACCOMPLISHMENTS. FAILURE TO SUBMIT A FINAL REPORT WILL RESULT IN AUTOMATIC DISQUALIFICATION FROM SUBMITTING A GRANT APPLICATION TO AICR FOR TWO YEARS. FINAL FINANCIAL REPORT: A FINAL REPORT OF EXPENDITURES MUST BE SUBMITTED WITHIN THREE MONTHS OF THE TERMINATION OF THE GRANT, TOGETHER WITH THE REFUND OF ANY UNSPENT FUNDS. UNSPENT FUNDS FROM AN EXISTING GRANT MAY ONLY BE CARRIED FORWARD AS A NO-COST EXTENSION TO THE GRANT TERM WITH THE WRITTEN PERMISSION OF AICR. BEFORE GRANT RECOMMENDATIONS ARE PRESENTED TO THE BOARD OF DIRECTORS FOR APPROVAL, ALL APPLICANTS ARE CHECKED AND CLEARED AGAINST THE FOLLOWING TERRORIST WATCH LISTS: SPECIALLY DESIGNATED NATIONALS (SDN), STATE DEPARTMENT TERRORIST EXCLUSIONS LIST, UNITED NATIONS CONSOLIDATED LIST WITH RESPECT TO AL-QAIDA, THE TALIBAN, AND OSAMA BIN LADEN, AND THE EUROPEAN UNION TERRORIST LIST. PART I, LINE 3: GRANTMAKING EXPENDITURES ARE RECORDED ON THE ACCRUAL BASIS. PART III ACCOUNTING METHOD: X X X X 1 DIRECT RESPONSE CONSULTING 7918 JONES BRANCH DRIVE MCLEAN VA 22102 DIRECT MAIL 0 3559251 303938 3255313 INFOCISION MANAGEMENT CORP 325 SPRINGSIDE DR AKRON OH 44144 PHONE 0 115590 49390 66200 3674841 353328 3321513 AL AK AZ AR CA CO CT DE FL GA HI ID IL IN IA KS KY LA ME MD MA MI MN MS MO MT NE NV NH NJ NM NY NC ND OH OK OR PA RI SC SD TN TX UT VT VA WA WV WI WY SCHEDULE G, PART I: PAYMENTS TO INFOCISION MANAGEMENT CORPORATION INCLUDE FEES FOR PROFESSIONAL FUNDRAISING SERVICES PLUS FUNDRAISING EXPENSES - LIST DEVELOPMENT, DATA PROCESSING, PRINTING AND MAILHOUSE FEES. INVOICES CLEARLY DISTINGUISH FUNDRAISING FEES FROM FUNDRAISING EXPENSES. ADDITIONAL COSTS, SUCH AS CAGING, BANK CHARGES, OTHER DATA PROCESSING AND POSTAGE ASSOCIATED WITH PHONE SOLICITATIONS ARE PAID DIRECTLY TO THE VENDOR AND THEREFORE NOT INCLUDED IN SCHEDULE G, COLUMN (V) AMOUNTS. PAYMENTS TO DIRECT RESPONSE CONSULTING SERVICES ARE FOR PROFESSIONAL FUNDRAISING SERVICES ONLY. ALL OTHER FUNDRAISING EXPENSES ASSOCIATED WITH DIRECT MAIL FUNDRAISING ARE PAID DIRECTLY TO THE VENDOR PROVIDING THE SERVICE AND THEREFORE NOT INCLUDED IN SCHEDULE G, COLUMN (V) AMOUNTS. 1 THE UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER (UT SOUTHWESTERN) 5323 HARRY HINES BOULEVARD DALLAS TX 75390 752556007 501(C)(3) 165000 0 RESEARCH THE OHIO STATE UNIVERSITY 281 W LANE AVE COLUMBUS OH 43210 316025986 501(C)(3) 247500 0 RESEARCH BRIGHAM AND WOMEN'S HOSPITAL INC 75 FRANCIS STREET BOSTON MA 02115 042312909 501(C)(3) 165000 0 RESEARCH 3 0 PART I, LINE 2: PROGRESS REPORT: AT THE END OF THE FIRST YEAR OF ANY TWO-YEAR GRANT, THE PRINCIPAL INVESTIGATOR MUST SUBMIT A PROGRESS REPORT, INCLUDING ABSTRACTS AND PUBLICATIONS OF RESEARCH SUPPORTED IN WHOLE OR IN PART BY AICR. AT THE DISCRETION OF AICR, FUNDS FOR THE SECOND YEAR OF THE GRANT MAY BE WITHHELD BASED ON THE PROGRESS REPORT OR IF PROGRESS REPORTS ARE NOT SUBMITTED. FINAL SCIENTIFIC REPORT: WITHIN THREE MONTHS OF THE COMPLETION OF THE GRANT PERIOD, AICR REQUIRES A FINAL COMPREHENSIVE REPORT TO OUTLINE THE PROJECT'S ACCOMPLISHMENTS. FAILURE TO SUBMIT A FINAL REPORT WILL RESULT IN AUTOMATIC DISQUALIFICATION FROM SUBMITTING A GRANT APPLICATION TO AICR FOR TWO YEARS. FINAL FINANCIAL REPORT: A FINAL REPORT OF EXPENDITURES MUST BE SUBMITTED WITHIN THREE MONTHS OF THE TERMINATION OF THE GRANT, TOGETHER WITH THE REFUND OF ANY UNSPENT FUNDS. UNSPENT FUNDS FROM AN EXISTING GRANT MAY ONLY BE CARRIED FORWARD AS A NO-COST EXTENSION TO THE GRANT TERM WITH THE WRITTEN PERMISSION OF AICR. BEFORE GRANT RECOMMENDATIONS ARE PRESENTED TO THE BOARD OF DIRECTORS FOR APPROVAL, ALL APPLICANTS ARE CHECKED AND CLEARED AGAINST THE FOLLOWING TERRORIST WATCH LISTS: SPECIALLY DESIGNATED NATIONALS (SDN), STATE DEPARTMENT TERRORIST EXCLUSIONS LIST, UNITED NATIONS CONSOLIDATED LIST WITH RESPECT TO AL-QAEDA, THE TALIBAN, AND OSAMA BIN LADEN, AND THE EUROPEAN UNION TERRORIST LIST. X X X 0 0 0 0 0 0 0 0 0 DEIRDRE MCGINLEY-GIESER EXECUTIVE VP 175168 0 0 0 1052 0 0 0 17733 0 193953 0 0 0 JENNIFER MERCER SENIOR VP DEVELOPMENT 174757 0 0 0 239 0 0 0 18434 0 193430 0 0 0 NIGEL BROCKTON VP RESEARCH 148536 0 0 0 295 0 0 0 20966 0 169797 0 0 0 MICHAEL MCCARN CHIEF INFORMATION OFFICER 145026 0 0 0 822 0 0 0 23351 0 169199 0 0 0 PATRICIA BODENSTEDT VP FINANCE 151512 0 0 0 0 0 0 0 15390 0 166902 0 0 0 SCHEDULE J, PART II, COLUMN (B), LINE (1): MARILYN GENTRY (PRESIDENT, WCRF INTERNATIONAL): $101,236 MS. GENTRY'S COMPENSATION PACKAGE IS PAID BY WCRF INTERNATIONAL. AICR IS REQUIRED TO REPORT ALL COMPENSATION PAID TO MS. GENTRY BY ALL OF AICR'S AFFLILIATES. AICR DOES NOT PAY MS. GENTRY FOR HER ROLE AS PRESIDENT OF AICR. DIRECT RESPONSE CONSULTING SERVICES 100% CONTROLLED ENTITY OF ONE OF THE FOUNDERS OF AICR 407244 FUNDRAISING CONSULTANT 0 FORM 990, PART III, LINE 4A, CONTINUED. CANCER HEALTH CHECK AN ONLINE ASSESSMENT TOOL TO HELP INDIVIDUALS UNDERSTAND HOW THE LIFESTYLE CHOICES THEY MAKE EVERY DAY CAN REDUCE THEIR RISK FOR CANCER. THIS SIMPLE AND EASY TOOL MEASURES INDIVIDUAL LIFESTYLE CHOICES, LIKE DIET AND EXERCISE HABITS, AGAINST AICR'S EVIDENCE-BASED 10 CANCER PREVENTION RECOMMENDATIONS. AFTER USERS ANSWER A BRIEF SERIES OF QUESTIONS, THEY IMMEDIATELY RECEIVE A SUMMARY OF RESULTS THAT SHOW AREAS WHERE THEY ARE DOING WELL AND WHERE THERE ARE AREAS FOR IMPROVEMENT. THIS IS AN APPROACHABLE TOOL THAT IS USED BY BOTH THE GENERAL PUBLIC AND BY HEALTH-CARE PROVIDERS. THIS INNOVATIVE TOOL LAUNCHED IN FEBRUARY 2020 WAS AWARDED GOLD/FIRST PLACE IN THE DIGITAL HEALTH RESOURCES/TOOL CATEGORY IN THE 2020 FALL DIGITAL HEALTH AWARDS. THERE WAS A TOTAL OF 15,918 USERS/E-MAILS COLLECTED IN FY2023 LIVING WITH CANCER AND BEYOND: CANCER RESOURCE PROGRAM AICR OFFERS A FREE BOOKLET OF ADVICE FOR NEWLY DIAGNOSED CANCER PATIENTS AND THEIR LOVED ONES. DEVELOPED WITH A TEAM OF PHYSICIANS, NURSES, DIETITIANS, PSYCHOLOGISTS AND CANCER PATIENTS, CANCER RESOURCE LAYS OUT INFORMATION PATIENTS NEED, INCLUDING QUESTIONS TO ASK YOUR DOCTOR, TREATMENT OPTIONS, WHERE TO FIND HELP, NUTRITION DURING TREATMENT AND MUCH MORE. AICR STAFF CAN CREATE CUSTOMIZED PACKETS FOR ANY CANCER BY INCLUDING SPECIFIC, DETAILED AND UP-TO-DATE PRINTOUTS ABOUT THE RELEVANT CANCER. REQUESTS FOR EACH PACKET ARE FILLED IMMEDIATELY TO GET THIS VITAL INFORMATION TO THOSE WHO NEED IT AS QUICKLY AS POSSIBLE. CANCER RESOURCE IS ALSO AVAILABLE IN SPANISH, WHICH INCREASES ACCESS TO THIS INFORMATION EVEN FURTHER AS A FREE DOWNLOADABLE ON AICR'S ONLINE STORE. IN FY23 THERE WERE A TOTAL OF 172 DOWNLOADS OF CANCER RESOURCE IN SPANISH, 4 DOWNLOADS IN ENGLISH AND 128 CANCER RESOURCE BOOKS WERE SOLD IN FY23. AICR'S HEALTH PROFESSIONAL AND EDUCATOR COMMUNITY AICR'S HP COMMUNITY PROVIDES AN ONLINE DESTINATION FOR HEALTH PROFESSIONALS, FEATURING A WEALTH OF INTERACTIVE TOOLS, CONTINUING EDUCATION OPPORTUNITIES AND PRACTICAL EVIDENCE-BASED RESOURCES FOR PATIENTS AND CLIENTS. PROGRAMS FOR CANCER SURVIVORS THE OVERALL AGING OF THE UNITED STATES POPULATION AND CHANGING PREVALENCE OF RISK FACTORS, INCLUDING OBESITY, HAVE INCREASED THE INCIDENCE OF MANY TYPES OF CANCER WHILE ADVANCES IN THE EARLY DETECTION AND TREATMENT OF CANCER HAVE LED TO REDUCED CANCER MORTALITY. THESE FACTORS HAVE COMBINED TO DRAMATICALLY INCREASE THE NUMBER OF CANCER SURVIVORS. NEARLY 18.3 MILLION PEOPLE IN THE US WERE LIVING WITH A HISTORY OF A CANCER DIAGNOSIS AS OF JANUARY 2022. THIS NUMBER IS PROJECTED TO GROW TO MORE THAN 26 MILLION BY 2040. DURING FY23, AICR PROACTIVELY FUNDED RESEARCH, DEVELOPED EVIDENCE-BASED INFORMATION AND CONTRIBUTED TOOLS, RESOURCES AND PROGRAMS THAT ARE ATTUNED TO THIS GROWING POPULATION. THE NEW AMERICAN PLATE COOKBOOK TO PLACE AICR'S MESSAGE ABOUT LOWERING CANCER RISK IN A COMPREHENSIVE AND HANDSOMELY PRODUCED FORMAT, AICR'S NEW AMERICAN PLATE COOKBOOK (PUBLISHED BY THE UNIVERSITY OF CALIFORNIA PRESS) IS AVAILABLE IN BOOKSTORES. ALMOST 35,000 COPIES HAVE BEEN SOLD, AND ALL ROYALTIES SUPPORT AICR CANCER RESEARCH. CONFERENCES AND EXHIBITS IN FY23, AICR STAFF ATTENDED, PRESENTED, NETWORKED, EXHIBITED AND/OR DISTRIBUTED MATERIALS AT VARIOUS VIRTUAL CONFERENCES AND ANNUAL MEETINGS. EXTERNAL RELATIONS IN FY23, AICR BUILT DEEPER RELATIONSHIPS WITH KEY NATIONAL, REGIONAL AND LOCAL STAKEHOLDER ORGANIZATIONS TO LEVERAGE THESE PARTNERSHIPS AND ENSURE OUR EVIDENCE-BASED MESSAGES AND EDUCATIONAL RESOURCES ARE UNDERSTOOD AND UTILIZED. AICR PROACTIVELY JOINED ADDITIONAL ORGANIZATIONS' COMMITTEES AND SERVED ON ADVISORY PANELS, WORK GROUPS AND EXPERT FORUMS TO BUILD VISIBILITY AND AWARENESS OF OUR MISSION. MEDIA PROGRAM AICR HAD SOLID MEDIA COVERAGE IN NATIONAL PRINT AND ONLINE OUTLETS AS WELL AS TV AND RADIO STATIONS. FORM 990, PART III, LINE 4B, CONTINUED. ON OCTOBER 13, 2022, THE CUP WAS RELAUNCHED DURING A WEBINAR THAT PRESENTED THE REFOCUSED GLOBAL CANCER UPDATE PROGRAM (CUP-GLOBAL), INTRODUCED THE NEW CUP GLOBAL PANEL INCLUDING PROFESSOR LORD JOHN KREBS AND PROFESSOR MATTY WEIJENBERG (THE NEW GLOBAL CANCER UPDATE PROGRAM PANEL CHAIR AND DEPUTY CHAIR, RESPECTIVELY), OUTLINED THE ROLE OF THE EXPERT COMMITTEES AND HIGHLIGHTED THE KEY GOALS AND PRIORITIES FOR THIS NEW AND EXCITING FUTURE FOR OUR FLAGSHIP RESEARCH PROGRAM. AICR ANNUAL RESEARCH CONFERENCE THE 2022 AICR RESEARCH CONFERENCE: DIET, OBESITY, PHYSICAL ACTIVITY AND CANCER WAS HELD OCTOBER 31 TO NOVEMBER 2, 2022, AT THE LANSDOWNE RESORT & SPA IN LEESBURG, VA. THE 2022 RESEARCH CONFERENCE WAS A HYBRID EVENT WITH BOTH A FULLY VIRTUAL OPTION AND AN IN-PERSON PROGRAM. KEYNOTE ADDRESS: DAVID ROBERT GRIMES, PHD: STEMMING A RISING TIDE OF CANCER MISINFORMATION PLENARY SESSIONS: TRUSTED SOURCES: COMBATTING MISINFORMATION THROUGH EFFECTIVE EVIDENCE-BASED COMMUNICATION ENHANCING CANCER THERAPY THROUGH CONVERGING INNOVATIONS IN LIFESTYLE AND ONCOLOGY RESEARCH THE ROLE OF LIFESTYLE IN ELEVATED GENETIC RISK DEVELOPING AND IMPLEMENTING CANCER PREVENTION, TREATMENT AND SURVIVORSHIP GUIDELINES SPEAKERS AND TOPICS: SYLVIA CHOU, PHD, MPH: COMBATTING CANCER MISINFORMATION IN A COMPLEX COMMUNICATION ECOSYSTEM DR. ROBERT MILLER, MD, FACP, FASCO, FAMIA: ONE-TO-ONE AND ONE-TO-MANY: AN ONCOLOGIST'S ROLE IN CONFRONTING CANCER MISINFORMATION KAREN BASEN-ENGQUIST, PHD, MPH: ACTIVE LIVING AFTER CANCER, A PHYSICAL ACTIVITY PROGRAM FOR CANCER SURVIVORS PARTNERING WITH COMMUNITY ORGANIZATIONS SAMUEL ORANGE, PHD: FEASIBILITY OF HOME-BASED, VIRTUALLY DELIVERED, GROUP EXERCISE FOR OLDER PATIENTS WITH PRIMARY LIVER CANCER (TELEX-LIVER CANCER): INTERIM ANALYSIS SCHEREZADE MAMA, DRPH: DESIGNING A MULTICOMPONENT PHYSICAL ACTIVITY INTERVENTION TO MEET THE UNIQUE NEEDS OF RURAL CANCER SURVIVORS UNDERGOING RADIATION THERAPY NEIL IYENGAR, MD AND RICHARD SIMPSON, PHD, FACSM: ENHANCING CANCER THERAPY THROUGH CONVERGING INNOVATIONS IN LIFESTYLE AND ONCOLOGY RESEARCH JUSTIN BROWN, PHD: ADAPTIVE RANDOMIZATION OF AEROBIC EXERCISE DURING CHEMOTHERAPY FOR COLON CANCER GRAEME KOELWYN, PHD, MS: HEART DISEASE AND CANCER: A TWO-WAY RELATIONSHIP LEWIS CANTLEY, MD, PHD: DIETARY INTERVENTION TO IMPROVE CANCER THERAPY JESSICA FESSLER, PHD: TARGETING THE MICROBIOTA-IMMUNE AXIS THROUGH DIET TO IMPROVE CANCER IMMUNOTHERAPY GERARDO MACKENZIE, PHD: LIVER SAFETY PROFILE OF A KETOGENIC DIET IN COMBINATION WITH GEMCITABINE IN PANCREATIC TUMOR-BEARING MICE ADAM NELCZYK, MS: FRIED CURED BACON AND HISTAMINERGIC SIGNALING: NOVEL INSIGHTS INTO THE IMPACT OF DIET ON THE DORMANT BREAST CANCER MICROENVIRONMENT ALANA ARNONE, MS: ENDOCRINE-TARGETING THERAPY SHIFTS THE BREAST MICROBIOME TO REDUCE ESTROGEN-RECEPTOR-A BREAST CANCER RISK CORNELIA ULRICH, PHD: PRECISION EXERCISE INTERVENTION IN PRIMARY AND SECONDARY LUNG CANCER PATIENTS UNDERGOING SURGERY: RESULTS FROM A PHASE III PEP STUDY TRIAL CHELSEA GOODENOUGH, PHD: BIOMARKERS OF CELLULAR SENESCENCE AND INFLAMMATION ASSOCIATED WITH EXERCISE CAPACITY AMONG ADULT SURVIVORS OF CHILDHOOD CANCER HEMANGI MAVADIYA, RD: RACIAL DISPARITY IN DIET RELATED PERCEPTIONS AND BEHAVIORS AMONG CANCER SURVIVORS KRISTY BROWN, PHD, AND CARRIE DANIEL-MACDOUGALL, PHD, MPH: THE ROLE OF LIFESTYLE IN ELEVATED GENETIC RISK LORELEI MUCCI, SCD: CAN THE INHERITED SUSCEPTIBILITY OF PROSTATE CANCER BE MODIFIED? (VIRTUAL) KRISTY A. BROWN, PHD: OBESITY IN BRCA MUTATION CARRIERS - PENETRATING INSIGHTS FROM MECHANISTIC STUDIES EDUARDO VILAR-SANCHEZ, MD, PHD: EXERCISE FOR CANCER PREVENTION IN LYNCH SYNDROME PATIENTS (VIRTUAL) JUSTIN GREGG, MD: COFFEE INTAKE, CAFFEINE METABOLISM GENOTYPE, AND SURVIVAL AMONG MEN WITH PROSTATE CANCER GABE CANALES: PATIENT ADVOCATES - AGENTS FOR CHANGE IN CANCER CARE AND RESEARCH DAWN MUSSALLEM, DO: THE EVOLVING ROLE FOR PATIENT ADVOCATES IN EVERY PHASE OF LIFESTYLE-RELATED CANCER RESEARCH WENDY K.D. SELIG, MS: IMPLEMENTATION OF PATIENT INVOLVEMENT IN CLINICAL CANCER RESEARCH: A PHILANTHROPIC FUNDERS APPROACH KAREN COLLINS, MS, RDN, CDN, FAND: DIETARY PATTERN RESEARCH AND RECOMMENDATIONS - EVIDENCE, GAP, AND COMMUNICATION SHERRY SHEN, MD: INSULIN-LOWERING DIETS: KETO AND LOW-CARBOHYDRATE DIETARY PATTERNS (VIRTUAL) ESTHER FARLEY, RN: PLANT-BASED DIETARY PATTERNS IN CANCER INCIDENCE AND MORTALITY - IMPACT AND CHALLENGES CLIFF HUDIS, MD: THE ROLE OF PROFESSIONAL SOCIETIES IN REDUCING CANCER RISK MARYAM LUSTBERG, MD, MPH: OPTIMIZING CANCER SURVIVORSHIP CARE DELIVERY: HOW CAN WE DO BETTER? ANN PARTRIDGE, MD, MPH: HARNESSING TECHNOLOGY IN PATIENT CENTERED CANCER CARE AICR TOWNHALL AICR HOSTED A TOWNHALL FOR PUBLIC ENGAGEMENT. DR. ETAN ORGEL AND DR. DAWN MUSSALLEM WERE THE FEATURED SPEAKERS FOR THE MEETING ON JUNE 14, 2023. EXTERNAL EVENTS AICR VP OF RESEARCH PRESENTED A GUEST LECTURE ON "NUTRITION AND CANCER - DISTINGUISHING EVIDENCE FROM OPINION IN CANCER PREVENTION AND SURVIVORSHIP" FOR THE NUTR305 COURSE, TUFTS UNIVERSITY, BOSTON, NOVEMBER 9, 2022. AICR VP OF RESEARCH PRESENTED A POST-CONFERENCE WORKSHOP ON "CANCER PREVENTION AND SURVIVORSHIP - TRANSLATING EVIDENCE TO EFFECTIVE LIFESTYLE MEDICINE PROGRAMS" AT THE AMERICAN COLLEGE OF LIFESTYLE MEDICINE CONFERENCE, ORLANDO, NOVEMBER 16, 2022. AICR VP OF RESEARCH PARTICIPATED IN THE ROUND TABLE DISCUSSION TO LAUNCH THE USDA'S NEW NUTRITION RESEARCH INITIATIVE: "AGRICULTURAL SCIENCE CENTER OF EXCELLENCE FOR NUTRITION AND DIET FOR BETTER HEALTH (ASCEND FOR BETTER HEALTH)," WEBINAR, DECEMBER 5, 2022. AICR VP OF RESEARCH PRESENTED A TALK ON "SCIENTIFIC RESEARCH ON LIFESTYLE CHOICES TO REDUCE YOUR CANCER RISK" CANCER HACKER LAB, PROSTATE CANCER LAB MEETING (VIRTUAL), JANUARY 18, 2023. AICR VP OF RESEARCH PRESENTED DURING A SYMPOSIUM ON "MEET THE FUNDERS: FUNDING OPPORTUNITIES FOR TRANSLATING BEHAVIORAL MEDICINE EVIDENCE INTO IMPACT" AT THE SOCIETY FOR BEHAVIORAL MEDICINE 44TH ANNUAL MEETING PHOENIX, AZ, APRIL 28, 2023. AICR VP OF RESEARCH PRESENTED TWO TALKS AT THE OGDEN SURGICAL-MEDICAL SOCIETY ANNUAL MEETING, OGDEN, UTAH: 1) "WHAT'S NEW IN MY SPECIALTY? BREAST CANCER PREVENTION AND 2) "CANCER PREVENTION RECOMMENDATIONS," OGDEN, UT, MAY 18 2023. RESEARCH PUBLICATIONS MANOCHA A, BROCKTON NT, COOK L, KOPCIUK KA. LOW SERUM VITAMIN D ASSOCIATED WITH INCREASED TUMOR SIZE AND HIGHER GRADE IN PREMENOPAUSAL CANADIAN WOMEN WITH BREAST CANCER. CLINICAL BREAST CANCER. 2023 AUG;23(6):E368-E376. AUNE D, MARKOZANNES G, ABAR L, BALDUCCI K, CARIOLOU M, NANU N, VIEIRA R, ANIFOWOSHE YO, GREENWOOD DC, CLINTON SK, GIOVANNUCCI EL, GUNTER MJ, JACKSON A, KAMPMAN E, LUND V, MCTIERNAN A, RIBOLI E, ALLEN K, BROCKTON NT, CROKER H, KATSIKIOTI D, MCGINLEY-GIESER D, MITROU P, WISEMAN M, VELIKOVA G, DEMARK-WAHNEFRIED W, NORAT T, TSILIDIS KK, CHAN DSM. PHYSICAL ACTIVITY AND HEALTH-RELATED QUALITY OF LIFE IN WOMEN WITH BREAST CANCER: A META-ANALYSIS. JNCI CANCER SPECTRUM. 2022 NOV 1;6(6). CARIOLOU M, ABAR L, AUNE D, BALDUCCI K, BECERRA-TOMS N, GREENWOOD DC, MARKOZANNES G, NANU N, VIEIRA R, GIOVANNUCCI EL, GUNTER MJ, JACKSON AA, KAMPMAN E, LUND V, ALLEN K, BROCKTON NT, CROKER H, KATSIKIOTI D, MCGINLEY-GIESER D, MITROU P, WISEMAN M, CROSS AJ, RIBOLI E, CLINTON SK, MCTIERNAN A, NORAT T, TSILIDIS KK, CHAN DSM. POSTDIAGNOSIS RECREATIONAL PHYSICAL ACTIVITY AND BREAST CANCER PROGNOSIS: GLOBAL CANCER UPDATE PROGRAMME (CUP GLOBAL) SYSTEMATIC LITERATURE REVIEW AND META-ANALYSIS. INTERNATIONAL JOURNAL OF CANCER. 2023 FEB 15;152(4):600-615. BECERRA-TOMS N, BALDUCCI K, ABAR L, AUNE D, CARIOLOU M, GREENWOOD DC, MARKOZANNES G, NANU N, VIEIRA R, GIOVANNUCCI EL, GUNTER MJ, JACKSON AA, KAMPMAN E, LUND V, ALLEN K, BROCKTON NT, CROKER H, KATSIKIOTI D, MCGINLEY-GIESER D, MITROU P, WISEMAN M, CROSS AJ, RIBOLI E, CLINTON SK, MCTIERNAN A, NORAT T, TSILIDIS KK, CHAN DSM. POSTDIAGNOSIS DIETARY FACTORS, SUPPLEMENT USE AND BREAST CANCER PROGNOSIS: GLOBAL CANCER UPDATE PROGRAMME (CUP GLOBAL) SYSTEMATIC LITERATURE REVIEW AND META-ANALYSIS. INTERNATIONAL JOURNAL OF CANCER. 2023 FEB 15;152(4):616-634. TSILIDIS KK, CARIOLOU M, BECERRA-TOMS N, BALDUCCI K, VIEIRA R, ABAR L, AUNE D, MARKOZANNES G, NANU N, GREENWOOD DC, GIOVANNUCCI EL, GUNTER MJ, JACKSON AA, KAMPMAN E, LUND V, ALLEN K, BROCKTON NT, CROKER H, KATSIKIOTI D, MCGINLEY-GIESER D, MITROU P, WISEMAN M, CROSS AJ, RIBOLI E, CLINTON SK, MCTIERNAN A, NORAT T, CHAN DSM POSTDIAGNOSIS BODY FATNESS, RECREATIONAL PHYSICAL ACTIVITY, DIETARY FACTORS AND BREAST CANCER PROGNOSIS: GLOBAL CANCER UPDATE PROGRAMME (CUP GLOBAL) SUMMARY OF EVIDENCE GRADING. INTERNATIONAL JOURNAL OF CANCER. 2023 FEB 15;152(4):635-644. FORM 990, PART III, LINE 4B, CONTINUED. CHAN DSM, VIEIRA R, ABAR L, AUNE D, BALDUCCI K, CARIOLOU M, GREENWOOD DC, MARKOZANNES G, NANU N, BECERRA-TOMS N, GIOVANNUCCI EL, GUNTER MJ, JACKSON AA, KAMPMAN E, LUND V, ALLEN K, BROCKTON NT, CROKER H, KATSIKIOTI D, MCGINLEY-GIESER D, MITROU P, WISEMAN M, CROSS AJ, RIBOLI E, CLINTON SK, MCTIERNAN A, NORAT T, TSILIDIS KK. POSTDIAGNOSIS BODY FATNESS, WEIGHT CHANGE AND BREAST CANCER PROGNOSIS: GLOBAL CANCER UPDATE PROGRAM (CUP GLOBAL) SYSTEMATIC LITERATURE REVIEW AND META-ANALYSIS. INTERNATIONAL JOURNAL OF CANCER. 2023 FEB 15;152(4):572-599. FORM 990, PART VI, SECTION B, LINE 11B THE 990 FORM IS PREPARED AND REVIEWED IN DETAIL BY KEY STAFF IN THE AICR ACCOUNTING DEPARTMENT. THE 990 FORM IS THEN REVIEWED BY AICR EXECUTIVE MANAGEMENT, RSM TAX AND THE LAW FIRM STEPTOE & JOHNSON. RSM TAX AND STEPTOE & JOHNSON BOTH CONDUCT DETAILED REVIEWS OF THE 990 FORM. ONCE THE 990 FORM AND ACCOMPANYING SCHEDULES ARE IN FINAL DRAFT FORM, THE AICR BOARD OF DIRECTORS ARE ASKED TO REVIEW AND PROVIDE FEEDBACK PRIOR TO THE FILING. FORM 990, PART VI, SECTION B, LINE 12C THE INSTITUTE'S BOARD OF DIRECTORS HAS A CONFLICT OF INTEREST POLICY IN EFFECT. A COPY OF THE POLICY IS PROVIDED TO EACH DIRECTOR, OFFICER AND STAFF MEMBER OF AICR WHO IS PRESENTLY SERVING IN A CAPACITY WHERE A CONFLICT OF INTEREST COULD ARISE. THE POLICY IS REVIEWED ANNUALLY. IF THE BOARD DETERMINES THAT CHANGES DO NOT NEED TO BE MADE, THE POLICY IS REAFFIRMED. NEW DIRECTORS, OFFICERS, AND STAFF MEMBERS ARE ADVISED OF THE POLICY IN EFFECT UPON TAKING OFFICE OR UPON THE START OF EMPLOYMENT, AS THE CASE MAY BE. SINCE FISCAL YEAR 2010, DIRECTORS, OFFICERS, EXECUTIVES, AND SENIOR LEVEL MANAGEMENT STAFF HAVE BEEN REQUIRED TO SIGN A "DECLARATION OF LACK OF CONFLICT OF INTEREST." THE POLICY PROVIDES THAT IN THE EVENT OF A CONFLICT OF INTEREST RELEVANT TO A MATTER REQUIRING ACTION BY THE BOARD, THE PERSON SHALL CALL IT TO THE ATTENTION OF THE BOARD (OR COMMITTEE OF THE BOARD, AS THE CASE MAY BE), AND SUCH PERSON SHALL NOT VOTE ON THE MATTER. THE PERSON HAVING A CONFLICT OF INTEREST SHALL PROVIDE THE BOARD (OR COMMITTEE OF THE BOARD, AS THE CASE MAY BE), WITH ANY AND ALL RELEVANT INFORMATION, AND SHALL RETIRE FROM THE ROOM IN WHICH THE BOARD (OR COMMITTEE OF THE BOARD, AS THE CASE MAY BE) IS MEETING CONCERNING SUCH MATTER, AND SHALL NOT PARTICIPATE IN THE FINAL DELIBERATION OR DECISION REGARDING THE MATTER UNDER CONSIDERATION. THE MINUTES OF THE MEETING OF THE BOARD (OR COMMITTEE OF THE BOARD, AS THE CASE MAY BE) SHALL REFLECT THAT THE CONFLICT OF INTEREST WAS DISCLOSED AND THAT THE INTERESTED PERSON WAS NOT PRESENT DURING THE FINAL DISCUSSION OF SUCH MATTER OR VOTE AND DID NOT VOTE ON SUCH MATTER. WHEN THERE IS A DOUBT AS TO WHETHER A CONFLICT OF INTEREST EXISTS, THE MATTER SHALL BE RESOLVED BY VOTE OF THE BOARD OF DIRECTORS (OR COMMITTEE OF THE BOARD, AS THE CASE MAY BE), EXCLUDING THE INTERESTED PERSON. FORM 990, PART VI, SECTION B, LINE 15 THE COMPENSATION COMMITTEE, THROUGH A RESOLUTION OF THE AICR BOARD OF DIRECTORS, IS RESPONSIBLE FOR SETTING THE COMPENSATION OF THE PRINCIPAL OFFICERS. THIS COMMITTEE CONDUCTS AN ANNUAL REVIEW OF PERFORMANCE AT THE END OF EACH CALENDAR YEAR AGAINST THE GOALS AND OBJECTIVES ESTABLISHED IN THE YEARLY BUDGETS, THE YEARLY OPERATION PLAN AND THE LONG-TERM STRATEGIC PLANS. INFORMATION UTILIZED IN DETERMINING COMPENSATION ADJUSTMENTS FOR THIS REPORTING PERIOD INCLUDE: 1) REPORT FROM THE EXECUTIVE TEAM FOR THE CALENDAR YEAR; 2) FISCAL YEAR PERFORMANCE AND EFFECTIVENESS ASSESSMENT REPORT; 3) HRA-NCA COMPENSATION SURVEY; 4) AMERICAN SOCIETY OF ASSOCIATION EXECUTIVES ASSOCIATION COMPENSATION AND BENEFITS REPORT; 5) GUIDESTAR COMPENSATION REPORT 5) NONPROFIT TIMES NONPROFIT SALARY AND BENEFITS REPORT. AFTER REVIEWING COMPENSATION STUDIES AND OTHER INDUSTRY INFORMATION, COMPENSATION IS DETERMINED AND AWARDED. INCREASES ARE CONSISTENT WITH COMPENSATION PAID BY ORGANIZATIONS SIMILAR TO AICR HAVING COMPARABLE RESPONSIBILITY AND DUTIES. INCREASES ARE DOCUMENTED AND A MEMO IS DRAFTED FROM THE COMPENSATION COMMITTEE TO THE SENIOR VICE PRESIDENT OF FINANCE, HUMAN RESOURCE FILE AND TO THE EXECUTIVES RECEIVING THE REVIEW INCLUDING THE INSTRUCTIONS AND DETAILS FOR THE COMPENSATION CHANGES. FORM 990, PART VI, SECTION C, LINE 19 ALL GOVERNING DOCUMENTS AND FINANCIAL STATEMENTS ARE AVAILABLE TO THE PUBLIC UPON REQUEST FOR THE SAME PERIOD OF DISCLOSURE AS SET FORTH IN SECTION 6104(D). FORM 990, PART XI, LINE 9: CHANGE IN VALUE OF SPLIT INTEREST AGREEMENT LIABILITY 69,342. NET GAIN ON INTEREST IN PERPETUAL TRUST 3,680. FORM 990, PART XII, LINE 2C: THE PROCESS FOR OVERSEEING THE AUDIT OF THE FINANCIAL STATEMENTS AND SELECTION OF AN INDEPENDENT ACCOUNTANT THAT AUDITED THE FINANCIAL STATEMENTS HAS BEEN CONSISTENT WITH PRIOR YEARS. WORLD CANCER RESEARCH FUND 140 PENTONVILLE RD LONDON UK N1 9FW AFFILIATED CHARITY UK AICR 1 WCRF (TRADING) LTD THE BROADGATE TOWER THIRD FLOOR PRIMROSE ST LONDON UK EC2A 2RS LIST RENTAL UK WORLD CANCER RESEARCH FUND C 0 CHARITABLE REMAINDER TRUST 1560 WILSON BOULEVARD SUITE 1000 ARLINGTON VA 22209 UNITRUST CA N/A T 0 PERPETUAL TRUST 1560 WILSON BOULEVARD SUITE 1000 ARLINGTON VA 22209 PERPETUAL TRUST PA N/A T 0 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1 0 0 WORLD CANCER RESEARCH FUND Q 145350 CASH WORLD CANCER RESEARCH FUND B 306775 CASH SCHEDULE R, PART IV, COLUMN (C): A CHARITABLE REMAINDER TRUST IS DOMICILED IN CALIFORNIA.