2024-04-15T09:44:45-00:00 2023-12-31 990 2023-01-01 843289802 ALS CURE PROJECT INC % Barron Wesenberg ALSC 9253215487 2808 LONGSPUR WAY Pleasanton CA 945665206 Barron Wesenberg Treasurer 2024-04-15 false Barron Wesenberg XXX-XX-XXXX true 3 AAL1 IAL1 2023 2023-04-26 12:10:37Z Mike Piscotty 2808 Longspur Way Pleasanton CA 94566 341443 false X alscure.net X 2019 CA The specfic purpose of the Organization shall include without limitation, to lead scientific research focused on the identification of Amyotrophic Lateral Scierosis ALS bio-markers and disease mechanism 8 8 0 20 0 143790 51469 0 0 14554 113020 158344 164489 240000 238000 0 0 0 4783 5563 6328 245563 244328 -87219 -79839 178157 98318 0 178157 98318 X This year the ALS Cure Project has funded multi-gene modeling at Stanford University and Sheffield University as funding research utilizing Sierram, the Lawerence Livermore Natonal Lab supercomputer, in multi-modal longitudinal modeling and physics-based modeling of TDP-43 protein and Organoid and Assembloid research. false false 20000 ALS Cure Project continued to fund the Physics based modeling project using the worlds fastest supercomputer at Lawerance Livermore Lab to help idenity and understand the ALS disease mechanism. The initial focus will be on the formation of the aberrant TAR DNA- binding protien 43 TDP-43 inclusions or cluster that transition into pathological, amyyloid-like fibrils 100000 ALS Cure Project funded seed research in Organoids and Assembloids from the 2023 Innovation Symposium that we host. The research will use cortico-motor assembloids to investigate the contribution of cortical neuronal hyperactivity to ALS phentypes, to ultimately pinpoint molecular pathways contributing to motor neuron degeneration 73000 The ALS Cure Project seeded 2 research project Barrow Neuro and Triparite selected from the ALS Innovation Symposim held virtual on November 17th and December 1stof 2021 that included 115 international ALS researchers from 10 nations where participants worked collaboratively in workshop styled breakouts to create the symposiums product. The event was also co-sponsored by Mitsubishi Tanabe Pharma America MTPA 45000 238000 true true false false false false false false false false false false false false false false false false false false false true false false true false false true false false false false false false false false false false false false false false false false false false false true 0 0 0 false false false false false false false false false false false false X 8 8 true false false false false false false true false false false true true true true false false false false false CA X X X Barron Wesenberg 9253215487 2808 Longspur Pleasanton CA 94566 X Mike Piscotty President 010.00 X X 0 0 0 Stephen Piscotty VIce President 001.00 X 0 0 0 Toni Eslick Secretary 006.00 X 0 0 0 James Gilbreth Fund Raising Director 006.00 X 0 0 0 Barron Wesenberg Treasurer 003.00 X 0 0 0 Andrew Woodward IT Communications Director 003.00 X 0 0 0 Dave Darby Corporate Sponsorship Director 003.00 X 0 0 0 Jim Poole Strategic Partnership Director 003.00 X 0 0 0 false false false 51469 51469 289974 51469 176954 113020 164489 238000 238000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2388 2388 2395 2395 0 0 0 0 0 0 0 0 1545 1545 0 244328 238000 1545 4783 178157 98318 178157 98318 0 0 X 133157 98318 45000 178157 98318 178157 98318 -79839 X false X false X false X 523773 404785 143790 51389 1123737 523773 404785 143790 51389 1123737 1123737 0 0 0 0 523773 404785 143790 51389 1123737 X 0.00000 0.00000 RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED Europe Including Iceland and Greenland Joint Research 50000 wire transfer 1 false false false false false false false Jim Poole Memorial Golf Tournament 63083 11383 51700 29000 15991 1310 Master Guitar Summit 60616 58279 2337 2337 3 166275 46460 119815 58090 11807 35015 18595 289974 116122 173852 87090 27798 35015 22242 172145 1707 true Livermore Lab Foundation 1111 Franklin St Oakland CA 94607 812567783 65000 Bio Markers Research and ALS Symposium Stanford University 450 Serra Mall Stanford CA 94035 860174371 73000 Multimodal Analysis Emory University 580566256 50000 Organoid and Assembloid Research University Medical Center Utrecht PO Box 85500 3508 GA Utrecht NL 50000 Organoid and Assembloid Research 4 Line 2 All progress/results are monitored by the research council. Funds are staggered and timed to release as activities occur Form 990, Part III, Line 4d Program Service Expenses 45,000, Grants and allocations 0, Revenue 0 ALS Innovation Symposium. Hosted over 100 international particpants representing 10 nations. The speakers and workshops identified and molded the research paths for the 2023 Roadmap to a Cure. Form 990, Part I, Line 1 The Specfic purpose of the Organization shall include without limitation, to lead scientific research on the indentification of Amyotrophic Lateral Scierssis ALS bio-markers and diease mechanism with the ultimate goal of finding a cure for ALS Form 990, Part III, Line 2 ALS Cure Project has funded Physics based modeling project using the worlds fastest supercomputer at Laverance Livermore Labs to help identify and understand the ALS disease mechanism. Addtionally we are funding Multi-modal and 3D functional modeling, and Organoids and Assembloids research. Form 990, Part VI, Section A, Line 8b Meeting minutes are taken at each meeting and distributed to all members for review Form 990, Part VI, Section B, Line 11b A full and unredacted copy of this form 990 including schedules will be provided to all board memebers via email for review before filing Form 990, Part VI, Section B, Line 12c Pursuant to the organizations Conflict of Interest Policy, all Board Members and Officers are required at minimum to confirm or report in writing the existence/absence of any conflicts of interest at the annual meeting. Also, Board members and Officers are required to inform the board, in writing, that a conflict of interest has arisen at any time during the year as well. Form 990, Part VI, Section C, Line 19 The organizations website alscure.org provides the email address of the President for inquiries from the general public and the organizations has a profile on guidestar.org that provides the tax documents of the organization Form 990, Part VI, Section A, Line 2 Mike Piscotty Family relationship to Stephen Piscotty Barron Wesenberg busines relationship to James Gilbreth.