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        <PersonNm>Kevin Churchwell MD</PersonNm>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>Douglas Vanderslice</PersonNm>
        <TitleTxt>Treasurer &amp; Trustee</TitleTxt>
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      <RltdOrgOfficerTrstKeyEmplGrp>
        <PersonNm>Michele Garvin Esq</PersonNm>
        <TitleTxt>Secretary &amp; Trustee</TitleTxt>
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        <PersonNm>Sandra Fenwick</PersonNm>
        <TitleTxt>Former President &amp; Trustee</TitleTxt>
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      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Part I, Line 4b</FormAndLineReferenceDesc>
        <ExplanationTxt>Children's Hospital Corporation, a related organization, made contributions to the supplemental non-qualified retirement plan for the individuals listed below. Contribution amounts are generally based on a percentage of compensation. Participants of the supplemental executive retirement plan are fully vested. All payments with respect to a participant's separation from service will be made in a single sum following the separation from service unless participant has elected to receive the accrued interest portion of his or her account in three annual installments. Contributions were for Children's Hospital Corporation employee benefits and not for Longwood Research Institute, Inc. Trustee or Officer of the Board services and/or responsibilities. During calendar year 2022, Children's Hospital Corporation made contributions to the supplemental non-qualified reitrement plan for the individuals below: Kevin Churchwell, MD received a contribution of $456,800 Douglas Vanderslice received a contribution of $242,524 Michele Garvin, Esq. received a contribution of $120,044 During calendar year 2022, the following individual received supplemental executive retirement plan distributions from Children's Hospital Corporation: Sandra Fenwick received a distribution of $958,796</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Part II</FormAndLineReferenceDesc>
        <ExplanationTxt>Compensation is for Children's Hospital Corporation executive/employee services; not for Longwood Research Institute, Inc. Trustee or Officer of the Board services.</ExplanationTxt>
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    </IRS990ScheduleJ>
    <IRS990ScheduleO documentId="RetDoc1044400001">
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section A, line 6</FormAndLineReferenceDesc>
        <ExplanationTxt>Children's Medical Center Corporation is the sole member of the organization.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section A, line 7a</FormAndLineReferenceDesc>
        <ExplanationTxt>The Children's Medical Center Corporation, as the sole member of the organization, elects the governing body of the organization.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section A, line 7b</FormAndLineReferenceDesc>
        <ExplanationTxt>Children's Medical Center Corporation is the sole member of the organization. As stated in the organization's By Laws, Children's Medical Center Corporation has the powers and rights: (1) to approve the annual operating and capital budgets of the Corporation; (2) to approve capital expenditures by the Corporation in excess of $150,000; (3) to approve long-range planning goals and objectives of the Corporation; (4) to approve the sale of any major portion of the Corporation's assets; (5) to approve the initiation of any fund raising program by the Corporation; (6) to approve the revision of policies with respect to personnel, public relations, fringe benefits or insurance by the Corporation; (7) to approve any new contracts by the Corporation with officers or key management personnel; (8) to approve any substantial increase by the Corporation in the compensation of employees or officers; (9) to approve any lease of equipment or real estate by the Corporation; (10) to approve any change in insurance coverage by the Corporation, whether malpractice, property, director/officer or otherwise; (11) to approve any incurrence of long-term indebtedness by the Corporation; (12) to approve any change in independent certified public accountants by the Corporation; (13) to approve any change in accounting practice by the Corporation; (14) to approve any change in bank accounts by the Corporation or persons authorized to sign checks on such accounts; (15) to approve any contracts involving an annual payment of more than $5,000 by the Corporation; (16) to approve any major change in significant suppliers; (17) to approve the entry into any new line of business by the Corporation.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section B, line 11b</FormAndLineReferenceDesc>
        <ExplanationTxt>The Form 990 tax return was prepared by the Children's Hospital staff and reviewed by the Chief Financial Officer &amp; General Counsel, along with the outside accounting firm of Ernst &amp; Young. A copy was made available to the Board prior to filing.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section B, line 12c</FormAndLineReferenceDesc>
        <ExplanationTxt>Longwood Research Institute, Inc. adopts the Conflict of Interest Policy in the form adopted and maintained by the Children's Hospital Corporation, as from time to time in effect. The Organization's Conflict of Interest and Commitment policy applies to all trustees, Trust Board members, members of the medical or research staff, faculty, fellow, resident, student, visiting faculty or scientist, consultant, volunteers and employees of the Hospital. Trustees, chiefs of service and division chiefs, senior directors and others who exercise influence over important strategic, business and purchasing decisions of the Hospital are required to complete an annual conflict of interest disclosure questionnaire about their financial interests and outside activities. If an expected questionnaire is not returned, the Compliance Officer notifies the individual's supervisor or the CEO or COO, and repeated requests for the completed questionnaire are made until the questionnaire is completed. Responses are reviewed by the Compliance Officer and any potential conflicts are discussed with the Office of General Counsel and/or the individual's supervisor; any actual or potential conflicts are managed by termination of the conflict, management of the conflict, recusal, disclosure, review, or a combination thereof. Outside interests and outside activities may be permitted as long as the Hospital, Medical Center or Trust determines that such interests and activities are consistent with the policies of the Hospital, Medical Center or Trust and the Hospital, Medical Center or Trust Board member, medical staff member or employee involved does the following: 1. discloses the fact that he/she has a financial interest or a consultative role in or with a person or company with which the Hospital, Medical Center or Trust is doing or is thinking of doing business; and 2. refrains from voting or exercising any personal influence whatsoever in the selection of a person or company to do business with the Hospital, Medical Center or Trust with whom or in which he/she has a financial interest or a consultative role; and 3. avoids any active participation in any financial negotiations between the Hospital, Medical Center or Trust and the person or company with whom or in which he/she has a financial interest or consultative role; and 4. does not permit such outside interests or activities to absorb such amounts of his/her time and effort as to make it impractical for them to fulfill their assigned responsibilities at the Hospital, Medical Center or Trust; and 5. does not permit such outside interests or activities to compromise or appear to compromise the name or reputation of the Hospital, Medical Center or Trust.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section B, line 15</FormAndLineReferenceDesc>
        <ExplanationTxt>The organization does not have any employees and does not compensate its Trustees or Officers of the Board.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VI, Section C, line 19</FormAndLineReferenceDesc>
        <ExplanationTxt>Longwood Research Institute, Inc. adopts the Code of Conduct, Conflict of Interest Policy, and the Compliance Manual, in the form adopted and maintained by the Children's Hospital Corporation, as from time to time in effect. Children's Hospital posts its Code of Conduct (which incorporates the Conflict of Interest Policy) and its Compliance Manual (which includes a summary of the Conflict of Interest Policy) on its external website and these are also available from the Compliance Office or the Office of General Counsel. Governing documents are not posted publicly but are available from the Hospital upon request and are also filed with the Massachusetts Secretary of State, where they are available to the public. Financial statements are available upon request.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part VII, Section A</FormAndLineReferenceDesc>
        <ExplanationTxt>The individuals, who have compensation from related organizations, listed in Column E, spend the remainder of their full time hours working for Children's Medical Center and its other affiliates.</ExplanationTxt>
      </SupplementalInformationDetail>
      <SupplementalInformationDetail>
        <FormAndLineReferenceDesc>Form 990, Part I, Line 4 &amp; VI, Line 1b - Governing Body &amp; Management</FormAndLineReferenceDesc>
        <ExplanationTxt>The filing organization has one independent member of the governing body. The other members of the governing body are compensated by a related organization. However, the filing organization is part of an integrated delivery system of organizations, including Children's Hospital that has community boards. There has been no material change in the structure of the governing body since it applied for and received recognition of exempt status.</ExplanationTxt>
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