2024-08-02T11:07:14-04:00 2023-12-31 474306215 Mullins PC 7625 Wisconsin Avenue Bethesda MD 20814 990 2023-01-01 813557785 RUNX1 Foundation dba RUNX1 Research Program RUNX 1482 E Valley Rd Ste 137 Santa Barbara CA 93108 Katrin Ericson President Exe 8058804105 2024-08-02 true true John Mullins P01429307 2027706371 2024-08-02 2023 2024-08-08 14:25:15Z Katrin Ericson 1549012 false X www.runx1-fpd.org X 2016 CA See Schedule O. 3 2 6 34 0 0 670719 1542823 0 6189 0 670719 1549012 1477750 815318 0 929656 971170 0 221674 473026 283258 2880432 2069746 -2209713 -520734 807381 1031227 181668 926248 625713 104979 X See Schedule O. false false 600279 281875 2023 Independent grants include the continued support of two researchers at University of Pennsylvania: Dr. Nancy Speck ($175,000) in the optimization of RUNX1-FPD CHIP mouse models, and Dr. Ximena Jordan-Bruno, Biobanking Lead (60,000); and ongoing research with Dr. Morty Pontz at Childrens Hospital of Philadelphia CHOP ($46,875) 532398 250000 Sponsored Research. 2023 co-funding partnership with the National Institutes of Health, National Institute of Allergy and Infectious Disease (NIAID) and National Cancer Institute (NCI), this grant mechanism supports 2 projects with scientific investigators Dr. Zon and Dr. Cantor both at Boston Childrens Hospital and their collaborators at NIAID and NCI, respectively. The two projects are entitled, Rescue of RUNX1 deficiency phenotypes in RUNX1-FPD patients treated with imatini and Defining clonal and metabolic alterations in the evolution of RUNX1-FPD. 415271 195000 Sponsored Research. 2023 co-funding partnership with Alexs Lemonade Stand Foundation (ALSF) continued, $195,000 supported a wide array of ground breaking research projects spanning basic science honing in on gene regulatory networks affected by RUNX1 mutations, classification of RUNX1 variants via novel saturation mutagenesis methods, modeling clonal evolution driven by common secondary somatic mutations, development of clinical consensus guidelines for RUNX1-FPD and defining the role of NLRP3 inflammasome in RUNX1 deficiency. 106480 50000 Sponsored Research. 2022 Focused Impact Research (FIRE) grant program. Continued co-funding partnership with EP Evans Foundation supported two projects (Dr. Bick and Dr. Agarwal) aimed at determining the role of inflammation in the initiation and progression of hematologic malignancies driven by germline RUNX1 mutations. 81867 38443 Sponsored Research. 2022 Mark Foundation Cancer Research (MFCR) Seeking Transformational Research Venture (STRIVE) - Continued Grant partnership. Sponsoring Institutes include research by Dr. Lucio Castilla, University of Massachusetts Medical School. 188347 88443 1736295 true true false false false false false false false false false false false false true true true false false false false false false false false false false true false true false false false false false false false false false false false false false false false false false true 7 0 true 6 true false false false false false false false false false false false false X 3 2 true false false false false false false true true false false false false false false false false false CA X The Organization 8058804105 1482 E Valley Rd Ste 137 Santa Barbara CA 93108 Katrin Ericson President Executive Directo 40.00 0.00 X X 428910 0 19149 Alex Gonzalez Director of Development 40.00 0.00 X 161200 0 12896 Amanda Eggen Director of Patient Engagemen 40.00 0.00 X 141308 0 10505 Timothy Babich Chairperson 15.00 0.00 X X 0 0 0 Monica Babich Secretary Treasurer CFO 15.00 0.00 X X 0 0 0 731418 0 42550 3 false true false 9992 1532831 1542823 6189 6189 1549012 0 0 6189 815318 815318 428910 324020 22314 82576 389570 294301 20268 75001 47801 36111 2487 9203 59455 44915 3093 11447 45434 34323 2364 8747 15739 15739 36138 36138 23686 20001 3685 12249 12249 25182 19817 1073 4292 55245 41434 2762 11049 17125 12844 856 3425 4683 4683 Program Research 93211 93211 2069746 1736295 111777 221674 771163 157941 869068 32000 4218 4218 807381 1031227 33847 83032 699068 147821 144148 181668 926248 X 625713 104979 625713 104979 807381 1031227 -520734 0 X false true X true false X 2366353 1431309 5335888 670719 1542823 11347092 2366353 1431309 5335888 670719 1542823 11347092 3135796 8211296 961 671 201 6189 8022 11355114 0.72310 0.35870 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED EIDL Note Payable 144148 144148 X 1549012 1549012 1549012 2069746 2069746 2069746 Footnote for uncertain tax position under FIN 48 (Part X) The Organization has adopted the Financial Accounting Standards Board (FASB) Accounting Standards Codification (ASC) FASB ASC 740-10, Income Taxes, which prescribes measurement and disclosure requirements for current and deferred income tax provisions. The interpretation provides for a consistent approach in identifying and reporting uncertain tax provisions. It is managements belief that The Organization does not hold any uncertain tax positions. true Boston Childrens Hospital 300 Longwood Ave Boston MA 02115 042774441 501c3 250000 RiSE Grant Program University of Washington Medicine 4333 Brooklyn Ave NE Seattle WA 98195 916001534 501c3 30000 Research in partnership with ALSF Childrens Hospital of Philadelphia 3615 Civic Center Philadelphia PA 19101 232237932 501c3 46875 Independent RRP Grant Dana Farber Cancer Institute 450 Brookline Ave Boston MA 02215 042263030 501c3 45000 Research partnered with ALSF Albert Einstein College of Medicine 1300 Morris Park Ave Bronx NY 10461 830621846 501c3 30000 Research partnered with ALSF St Jude Childrens Research 262 Danny Thomas Place Memphis TN 381053678 620646012 501c3 30000 Research in partnership with ALSF Memorial Sloan Kettering Cancer Ctr 1275 York Avenue New York NY 10065 131624082 501c3 30000 Research in partnership with ALSF Regents of University of CA Med Sch 1855 Folsom St Ste 425 San Francisco CA 941034249 946036493 501c3 30000 Research in partnership with ALSF University of Mass Medical School 55 Lake Avenue Worcester MA 01655 043108190 501c3 38443 Research in partnership with MFCR University of Pennsylvania 338 South 19th Street Philadelphia PA 19103 231352685 501c3 235000 RRP Independent Grant Edward P Evans Foundation 300 Brickstone Square Ste 201 Andover MA 01810 256232129 501c3 50000 Research pship with EP Evans 11 X X false false false false false false false false false Katrin Ericson President Executive Director 307359 121551 19149 448059 Amanda Eggen Director of Patient Engagement 141308 10505 151813 Alex Gonzalez Director of Development 161200 12896 174096 Officer directors etc family relationship Part VI line 2 Timothy and Monica Babich, the two co-directors, are married. Form 990 governing body review Part VI line 11 The Voting Members of the Organization have reviewed the form 990 and all schedules and have unanimously agreed on its accuracy. All members have received a copy for their records. Governing documents etc available to public Part VI line 19 The Organization will publish financial information, governing documents and conflict of interest policy on the Organizations website. Part III response or note to any other line in Part III Part I - Summary and Part III - Organizations Mission StatementTo provide grants for relevant research projects to find a cure for RUNX1-FPD, to raise public awareness, and to strengthen the community by providing a forum to help connect, inform and educate RUNX1-FPD patients and their families.