2024-08-01T13:57:42-05:00 2023-12-31 990 2023-01-01 236434390 THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY WIST 2154956922 3601 SPRUCE STREET PHILADELPHIA PA 191044265 CONSTANTINE STOIOS CHIEF FINANCIAL OFFICER 2154956922 2024-08-01 0 X 2023 2024-08-08 14:25:15Z CONSTANTINE STOIOS 3601 SPRUCE STREET PHILADELPHIA PA 19104 199714000 0 X WWW.WISTAR.ORG X 1892 PA BIOMEDICAL RESEARCH WITH SPECIAL EXPERTISE IN CANCER RESEARCH AND VACCINE DEVELOPMENT (IMMUNOLOGY). 29 29 457 62 449000 0 72907000 70736000 4982000 4069000 8756000 100471000 4076000 5974000 90721000 181250000 0 0 0 0 32639000 35855000 0 0 1590000 52423000 55967000 85062000 91822000 5659000 89428000 381486000 402392000 83370000 80282000 298116000 322110000 X THE MISSION OF THE WISTAR INSTITUTE IS TO MARSHAL THE TALENTS OF OUTSTANDING SCIENTISTS THROUGH A HIGHLY ENABLED CULTURE OF BIOMEDICAL COLLABORATION AND INNOVATION IN ORDER TO SOLVE SOME OF THE WORLD'S MOST CHALLENGING AND IMPORTANT PROBLEMS IN THE FIELD OF CANCER AND IMMUNOLOGY, AND PRODUCE GROUND-BREAKING ADVANCES IN WORLD HEALTH. CONSISTENT WITH A PIONEERING LEGACY OF LEADERSHIP IN NOT-FOR-PROFIT BIOMEDICAL RESEARCH AND A TRACK-RECORD OF LIFE-SAVING CONTRIBUTIONS IN IMMUNOLOGY AND CELL BIOLOGY, THE WISTAR INSTITUTE AIMS TO PURSUE NOVEL AND COURAGEOUS RESEARCH PATHS TO LIFE SCIENCE DISCOVERY, AND TO ACCELERATE/POTENTIATE THE IMPACT OF THOSE DISCOVERIES BY SHORTENING THE PATH FROM BENCH TO BEDSIDE. 0 0 74515000 4069000 THE WISTAR INSTITUTE IS THE NATION'S FIRST INDEPENDENT NONPROFIT INSTITUTION DEVOTED EXCLUSIVELY TO FOUNDATIONAL BIOMEDICAL RESEARCH AND TRAINING. SINCE 1972, THE INSTITUTE HAS HELD NATIONAL CANCER INSTITUTE (NCI)-DESIGNATED CANCER CENTER STATUS. THROUGH A CULTURE AND COMMITMENT TO BIOMEDICAL COLLABORATION AND INNOVATION, WISTAR SCIENCE LEADS TO BREAKTHROUGH EARLY-STAGE DISCOVERIES. WISTAR SCIENTISTS ARE DEDICATED TO SOLVING SOME OF THE WORLD'S MOST CHALLENGING PROBLEMS IN THE FIELD OF CANCER AND IMMUNOLOGY, ADVANCING HUMAN HEALTH THROUGH EARLY-STAGE DISCOVERY AND TRAINING THE NEXT GENERATION OF BIOMEDICAL RESEARCHERS. THE WISTAR INSTITUTE INCLUDES THE ELLEN AND RONALD CAPLAN CANCER CENTER, AND THE VACCINE & IMMUNOTHERAPY CENTER. WISTAR SCIENTISTS BENEFIT FROM THE TECHNOLOGICAL SUPPORT AND STATE-OF-THE-SCIENCE INSTRUMENTATION PROVIDED BY THE INSTITUTE'S SHARED RESOURCES. WISTAR HAS A PROVEN TRACK RECORD OF SUCCESS IN VACCINE DISCOVERY THAT LED TO VACCINES AGAINST RUBELLA, RABIES, AND ROTAVIRUS. WISTAR'S HUBERT J.P. SCHOEMAKER EDUCATION AND TRAINING CENTER HAS LAUNCHED NEW COLLABORATIONS WITH LOCAL AND INTERNATIONAL INSTITUTIONS WITH THE GOAL OF EXPANDING LIFE SCIENCE EDUCATION IN PENNSYLVANIA AND BEYOND. WISTAR HAS A ROBUST RANGE OF STEM-BASED PROGRAMS FOCUSED ON INCREASING ACCESS TO LIFE SCIENCE CAREERS FOR UNDER-REPRESENTED COMMUNITIES INCLUDING NON-TRADITIONAL STUDENTS AND ADULT LEARNERS. WISTAR'S EDUCATION & TRAINING PROGRAMS SUPPORT STEM-BASED, BIOMEDICAL RESEARCH CAREER OPPORTUNITIES FOR HIGH SCHOOL, UNDERGRADUATE, GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS. 74515000 1 1 0 1 0 0 0 1 0 1 1 1 0 1 0 1 1 0 0 0 1 0 0 0 0 0 0 0 0 1 1 0 0 0 0 0 0 0 0 0 0 1 0 0 0 0 1 1 1 0 0 1 203 0 457 1 1 1 0 0 0 0 1 1 0 0 0 0 0 0 X 29 29 1 0 0 0 0 1 1 1 1 0 0 1 1 1 1 1 1 1 1 0 AL AR AZ CA CO CT FL GA HI IL KS KY MA MD ME MI MN MO MS NC ND NH NJ NM NY OH OK OR PA RI SC TN UT VA WA WI WV X CONSTANTINE STOIOS CHIEF FINANCIAL OFFICER 2154956922 3601 SPRUCE STREET PHILADELPHIA PA 191044265 RICHARD M HOROWITZ TRUSTEE - BOARD CHAIR 4.00 X X 0 0 0 STEVEN V ABRAMSON TRUSTEE 1.00 X 0 0 0 ELIZABETH MCKEE ANDERSON TRUSTEE 2.00 X 0 0 0 MAX BERGER APPOINTED DEC 2023 TRUSTEE 1.00 X 0 0 0 DOUGLAS S BRIGGS TRUSTEE 1.00 X 0 0 0 IRA BRIND TRUSTEE 1.00 X 0 0 0 RONALD CAPLAN TRUSTEE 2.00 X 0 0 0 SCOTT COOPER UNTIL SEP 2023 TRUSTEE 1.00 X 0 0 0 ARTHUR DANTCHIK TRUSTEE 1.00 X 0 0 0 SUSAN B DILLON PHD TRUSTEE 1.00 X 0 0 0 BRIAN H DOVEY UNTIL AUG 2023 TRUSTEE 2.00 X 0 0 0 DANIEL K FITZPATRICK TRUSTEE 1.00 X 0 0 0 JOHN FRY TRUSTEE 1.00 X 0 0 0 JOSEPH A GOLDBLUM TRUSTEE 2.00 X 0 0 0 PERRY A LERNER TRUSTEE 1.00 X 0 0 0 SUSAN S MCDONALD PHD TRUSTEE 2.00 X 0 0 0 ABRAHAM L MORRIS TRUSTEE 1.00 X 0 0 0 PATRICK OATES APPOINTED SEP 2023 TRUSTEE 1.00 X 0 0 0 ARTHUR M PAPPAS TRUSTEE 1.00 X 0 0 0 HELEN P PUDLIN ESQ TRUSTEE 1.00 X 0 0 0 SAMUEL V RHOADS TRUSTEE 1.00 X 0 0 0 ROBERT H ROCK TRUSTEE 1.00 X 0 0 0 GERALD B RORER TRUSTEE 1.00 X 0 0 0 ALEISTER SAUNDERS APPOINTED SEP 202 TRUSTEE 1.00 X 0 0 0 ADELE K SCHAEFFER TRUSTEE 1.00 X 0 0 0 MILTON S SCHNEIDER TRUSTEE 1.00 X 0 0 0 SQUIRE SERVANCE TRUSTEE 1.00 X 0 0 0 WILLIAM A SLAUGHTER TRUSTEE 1.00 X 0 0 0 JOY TAYLOR TRUSTEE 1.00 X 0 0 0 SOZI TULANTE APPOINTED MAR 2023 TRUSTEE 1.00 X 0 0 0 DANIEL H WHEELER UNTIL JUL 2023 TRUSTEE 2.00 X 0 0 0 EDWARD ZIFF PHD TRUSTEE 1.00 X 0 0 0 DARIO ALTIERI MD PRESIDENT & CEO, DIRECTOR WISTAR CANCER CENTER 55.00 X 695231 0 52240 DAVID B WEINER EXECUTIVE VICE PRESIDENT 55.00 X 474053 0 63822 HEATHER A STEINMAN VP FOR BUSINESS DEVELOP & ED TECH 55.00 X 332348 0 38587 JOSEPH TRAINOR UNTIL MAY 2023 CHIEF FINANCIAL OFFICER 55.00 X 130191 0 19215 JOANN MENDEL VICE PRESIDENT, HUMAN RESOURCES 55.00 X 223372 0 36635 GELVINA STEVENSON VP GEN COUNSEL, SECRETARY& GOV RELATIONS 55.00 X 361859 0 40228 MICHAEL CRISCUOLO VP, DEVELOPMENT 55.00 X 253281 0 58940 CONSTANTINE STOIOS BEGAN SEP 2023 CHIEF FINANCIAL OFFICER 55.00 X 89474 0 15518 LUIS MONTANER PROFESSOR VP, SCIENTIFIC OPERATIONS 55.00 X 398122 0 69802 MEENHARD HERLYN PROFESSOR 55.00 X 314306 0 65935 PAUL LIEBERMAN PROFESSOR 55.00 X 275087 0 57674 MAUREEN MURPHY PROFESSOR 55.00 X 252407 0 55028 HILDEGUND ERTL PROFESSOR 55.00 X 267406 0 44388 4067137 0 618012 74 0 1 0 THE ARTHUR JACKSON COMPANY 7025 WEST CHESTER PIKE UPPER DARBY PA 19082 JANITORIAL SERVICES 907000 ALLIED UNIVERSAL SECURITY SERVICES PO BOX 828854 PHILADELPHIA PA 191828854 SECURITY SERVICES 708000 ASCENDIA PHARMACEUTICALS INC 661 US HIGHWAY ONE NORTH BRUNSWICK NJ 08902 DEVELOPMENT SERVICES 596000 RIVERSIDE LAW LLP 175 STRAFFORD AVENUE SUITE 100 WAYNE PA 19087 LEGAL SERVICES 528000 TRIUMVIRATE ENVIRONMENTAL INC DEPT 106069 PO BOX 150502 HARTFORD CT 06115 ENVIRONMENTAL SOLUTIONS SERVICES 463000 16 61320000 9416000 598000 70736000 RESEARCH CONTRACT REVENUE 541700 4069000 4069000 4069000 9045000 9045000 5346000 5346000 432000 376000 56000 56000 56000 109514000 18088000 91426000 91426000 91426000 SALES OF SPECIALIZED SERVICES 541700 449000 449000 123000 123000 572000 181250000 4069000 449000 105996000 2884000 1285000 1287000 312000 24759000 19218000 4959000 582000 2147000 1770000 350000 27000 4348000 3134000 1077000 137000 1717000 1333000 344000 40000 1329000 1329000 215000 215000 268000 268000 591000 591000 4360000 2398000 1630000 332000 185000 1000 179000 5000 387000 279000 94000 14000 1416000 289000 1107000 20000 4702000 4453000 215000 34000 554000 467000 78000 9000 1323000 1160000 154000 9000 7549000 6620000 878000 51000 298000 298000 SUBAWARDS 19459000 19459000 LAB SUPPLIES AND EQUIPM 11442000 10843000 599000 STIPENDS 1425000 1425000 TUITION, HONRARIUM, AND 258000 237000 21000 206000 144000 44000 18000 91822000 74515000 15717000 1590000 3041000 4320000 24310000 11011000 26651000 24933000 20079000 19630000 459000 657000 4134000 4543000 195546000 103647000 93432000 91899000 157325000 194682000 31237000 28747000 20818000 21970000 381486000 402392000 20814000 16689000 9803000 10813000 52753000 52780000 83370000 80282000 X 204267000 224558000 93849000 97552000 298116000 322110000 381486000 402392000 X 89428000 -66841000 1407000 X 0 1 X 1 1 1 X 48234000 51614000 95470000 72907000 70736000 338961000 48234000 51614000 95470000 72907000 70736000 338961000 14160880 324800120 9938000 9496000 11446000 9829000 14823000 55532000 851000 216000 182000 113000 123000 1485000 395978000 20678000 0.82020 0.83120 X PART II, LINE 8 INCLUDES $5,346,000 LICENSING INCOME, $9,045,000 DIVIDENDS AND INTEREST, AND $432,000 RENT REVENUE. PART II, LINE 10 INCLUDES $123,000 MISCELLANEOUS INCOME (POWER REDUCTION REFUND AND OTHER MISCELLANEOUS REBATES). RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 1 1 0 0 0 0 1 268000 0 0 268000 0 PART II-B, LINE 1: THE WISTAR INSTITUTE ENGAGED THE SERVICES OF TWO LOBBYING FIRMS WHOSE RESPONSIBILITIES ARE TO PROVIDE GOVERNMENT RELATIONS SERVICES TO THE WISTAR INSTITUTE AT THE FEDERAL, STATE AND LOCAL LEVELS. DUTIES INCLUDE MONITORING AND TRACKING LEGISLATION WHICH MAY BE OF INTEREST TO THE WISTAR INSTITUTE, ARRANGING MEETINGS WITH LEGISLATORS AND ARRANGING VISITS OF LEGISLATORS TO THE WISTAR INSTITUTE, AND ASSISTING IN FINDING FUNDING SOURCES FOR PROGRAMS. IN ADDITION, A NUMBER OF WISTAR STAFF PARTICIPATE IN ADVOCACY ON A REGULAR BASIS BY PARTICIPATING IN VISITS TO LEGISLATIVE OFFICES IN HARRISBURG, PA AND BY HOSTING VISITS OF STATE AND FEDERAL LEGISLATORS TO THE WISTAR INSTITUTE. WE ALSO OCCASIONALLY ASK OUR BOARD, EMPLOYEES OR FRIENDS/VOLUNTEERS TO WRITE LETTERS OR CALL THEIR REPRESENTATIVES REGARDING LEGISLATION THAT MAY IMPACT WISTAR. X X X 0 58049000 2529000 12270000 1289000 71559000 71500000 1041000 -13297000 1195000 58049000 62934000 286000 9350000 1070000 71500000 54250000 41000 9591000 948000 62934000 45876000 28000 9161000 815000 54250000 0.66000 0.24000 0.10000 0 0 685000 685000 99257000 46235000 53022000 93885000 56209000 37676000 1719000 1203000 516000 91899000 ALTERNATIVE INVESTMENTS 28747000 F 28747000 BENEFICIAL INTEREST IN CHARITABLE REMAINDER TRUSTS 1133000 BENEFICIAL INTEREST IN PERPETUAL TRUSTS 18903000 INTEREST RATE SWAP 1934000 21970000 X 115152000 -66841000 816000 -66025000 181177000 73000 73000 181250000 91158000 376000 376000 90782000 1040000 1040000 91822000 PART III, LINE 1A: COLLECTIONS CONSIST OF FAMILY MEMORABILIA AND OTHER ARTIFACTS WHICH ARE NOT USED IN THE INSTITUTE'S OPERATIONS. PART III, LINE 4: THE INSTITUTE'S COLLECTIONS CONSTITUTE A HISTORY OF MEDICAL SCIENCE IN PHILADELPHIA AND THE HISTORY OF VACCINE DEVELOPMENT. THE MUSEUM COLLECTIONS ARE TIED TO OUR DEEDS OF TRUST AND HAVE SIGNIFICANT HISTORICAL VALUE, AS WISTAR WAS ESTABLISHED AS THE FIRST INDEPENDENT NONPROFIT BIOMEDICAL RESEARCH INSTITUTE IN THE COUNTRY. PART V, LINE 4: MANAGEMENT DETERMINES THE PRUDENT USE OF THE ENDOWMENT FUNDS TO SUPPORT GENERAL PURPOSES AND RESEARCH AND TRAINING PROGRAMS AS SPECIFIED BY THE VARIOUS ENDOWMENT PROGRAMS. PART X, LINE 2: THE INSTITUTE IS A NOT-FOR-PROFIT INSTITUTE WHICH HAS BEEN DETERMINED BY THE INTERNAL REVENUE SERVICE TO BE EXEMPT FROM FEDERAL INCOME TAXES UNDER SECTION 501(C)(3) OF THE INTERNAL REVENUE CODE (IRC). THE INSTITUTE ACCOUNTS FOR UNCERTAINTIES IN INCOME TAXES IN ACCORDANCE WITH AUTHORITATIVE GUIDANCE, WHICH PRESCRIBES A RECOGNITION THRESHOLD OF MORE-LIKELY-THAN-NOT TO BE SUSTAINED UPON EXAMINATION BY THE APPROPRIATE TAXING AUTHORITY. MEASUREMENT OF THE TAX UNCERTAINTY OCCURS IF THE RECOGNITION THRESHOLD HAS BEEN MET. MANAGEMENT BELIEVES THAT THERE WERE NO TAX UNCERTAINTIES THAT MET THE RECOGNITION THRESHOLD FOR THE YEAR 2023. PART XI, LINE 2D - OTHER ADJUSTMENTS: LOSS ON SPLIT-INTEREST AGREEMENTS 1,725,000. CHANGE IN CASH SURRENDER VALUE OF LIFE INSURANCE POLICIES 6,000. PENSION - NET GAIN 244,000. INTEREST RATE SWAP - NET LOSS -568,000. INVESTMENT MANAGEMENT FEES -591,000. PART XI, LINE 4B - OTHER ADJUSTMENTS: RENTAL EXPENSE -376,000. UNRELATED BUSINESS RECEIPTS 449,000. PART XII, LINE 2D - OTHER ADJUSTMENTS: RENTAL EXPENSES 376,000. PART XII, LINE 4B - OTHER ADJUSTMENTS: INVESTMENT MANAGEMENT AND CUSTODIAL FEES 591,000. UNRELATED BUSINESS REVENUES 449,000. CENTRAL AMERICA AND THE CARIBBEAN - ANTIGUA & BARBUDA, ARUBA, BAHAMAS, 0 0 INVESTMENTS 11787000 0 0 0 0 0 0 11787000 0 11787000 1 0 1 1 1 0 PART I, LINE 3 ALTHOUGH WISTAR MAINTAINS INTERESTS IN THESE FOREIGN CORPORATIONS AND PARTNERSHIPS, ITS OWNERSHIP PERCENTAGE DID NOT MEET THE THRESHOLD FOR REPORTING ON IRS FORM 5471 AND 8865. WISTAR MADE TRANSFERS TO FOREIGN CORPORATIONS THAT EXCEEDED THE THRESHOLD TO FILE FORM 926. X X X 0 1 X X X X 0 0 0 0 0 0 0 1 0 DARIO ALTIERI MD PRESIDENT & CEO, DIRECTOR WISTAR CAN 688373 0 0 0 6858 0 42900 0 9340 0 747471 0 0 0 DAVID B WEINER EXECUTIVE VICE PRESIDENT 387883 0 80500 0 5670 0 41310 0 22512 0 537875 0 0 0 LUIS MONTANER PROFESSOR VP, SCIENTIFIC OPERATIONS 254207 0 90500 0 53415 0 42100 0 27702 0 467924 0 0 0 GELVINA STEVENSON VP GEN COUNSEL, SECRETARY& GOV RELAT 350520 0 10500 0 839 0 39400 0 828 0 402087 0 0 0 MEENHARD HERLYN PROFESSOR 281090 0 30500 0 2716 0 41608 0 24327 0 380241 0 0 0 HEATHER A STEINMAN VP FOR BUSINESS DEVELOP & ED TECH 260551 0 71417 0 380 0 38172 0 415 0 370935 0 0 0 PAUL LIEBERMAN PROFESSOR 252900 0 20500 0 1687 0 36428 0 21246 0 332761 0 0 0 MICHAEL CRISCUOLO VP, DEVELOPMENT 252077 0 500 0 704 0 29280 0 29660 0 312221 0 0 0 HILDEGUND ERTL PROFESSOR 262997 0 500 0 3909 0 35133 0 9255 0 311794 0 0 0 MAUREEN MURPHY PROFESSOR 237250 0 14120 0 1037 0 33655 0 21373 0 307435 0 0 0 JOANN MENDEL VICE PRESIDENT, HUMAN RESOURCES 201323 0 20500 0 1549 0 26792 0 9843 0 260007 0 0 0 PART I, LINE 1A TAX INDEMNIFICATION AND GROSS-UP PAYMENTS INCLUDE TUITION BENEFITS. DISCRETIONARY SPENDING ACCOUNT INCLUDES SOCIAL CLUB DUES FOR CEO ONLY. ALL AMOUNTS INCLUDED IN TAXABLE COMPENSATION. PART I, LINE 1B TAX INDEMNIFICATION AND GROSS-UP PAYMENTS ARE PROVIDED WITH A WRITTEN POLICY. SOCIAL CLUB DUES ARE PROVIDED VIA EMPLOYMENT CONTRACT WITH CEO. PART I, LINE 7 NON-FIXED PAYMENTS, IN THE FORM OF BONUSES, ARE APPROVED BY THE BOARD EXECUTIVE EVALUATION AND COMPENSATION COMMITTEE. THE BONUSES ARE BASED ON PERFORMANCE INCLUDING LEADERSHIP. REVENUE IS NOT A BASIS FOR A BONUS. A PHILADELPHIA AUTHORITY FOR INDUSTRIAL DEVELOPMENT 232337287 2017-12-28 52857000 CAPITAL PROJECT FINANCING 0 0 0 B PHILADELPHIA AUTHORITY FOR INDUSTRIAL DEVELOPMENT 232337287 2017-12-28 4500000 CAPITAL PROJECT FINANCING LINE OF CREDIT 0 0 0 A 52857000 257000 52600000 2014 1 0 1 1 B 4500000 20000 4480000 2026 0 0 0 1 A 0 0 1 1 0 0.00000 0.00000 0.00000 0 0 1 B 0 0 1 1 0 0.00000 0.00000 0.00000 0 0 1 A 0 0 1 0 1 1 PNC BANK 10.000000000000 1 0 0 0 1 B 0 0 1 0 1 0 0 0 1 A 1 B 1 X 7 598000 NYSE 0 0 1 0 SCHEDULE M, PART I, LINE 9 THE NUMBER REPORTED IN COLUMN (B) LINE 9 IS THE NUMBER OF CONTRIBUTIONS. FORM 990, HEADER, LINE A THE INSTITUTE FILED TIMELY FORM 8868, APPLICATION FOR EXTENSION OF TIME TO FILE AN EXEMPT ORGANIZATION RETURN. FORM 990, PART VI, SECTION A, LINE 2 SUSAN DILLON (TRUSTEE) HAS A BUSINESS RELATIONSHIP WITH ELIZABETH MCKEE ANDERSON (TRUSTEE). FORM 990, PART VI, SECTION A, LINE 7A THE ACADEMY OF NATURAL SCIENCES AT DREXEL UNIVERSITY AND THE WISTAR FAMILY HAVE THE RIGHT TO DESIGNATE REPRESENTATION TO THE BOARD OF TRUSTEES. THE UNIVERSITY OF PENNSYLVANIA APPROVES APPOINTMENTS TO THE BOARD OF TRUSTEES UNDER THE INSTITUTE'S FOUNDING DEEDS OF TRUST. FORM 990, PART VI, SECTION A, LINE 7B THE ACADEMY OF NATURAL SCIENCES AT DREXEL UNIVERSITY AND THE WISTAR FAMILY HAVE THE RIGHT TO DESIGNATE REPRESENTATION TO THE BOARD OF TRUSTEES. THE UNIVERSITY OF PENNSYLVANIA APPROVES APPOINTMENTS TO THE BOARD OF TRUSTEES UNDER THE INSTITUTE'S FOUNDING DEEDS OF TRUST. FORM 990, PART VI, SECTION B, LINE 11B THE FORM 990 IS REVIEWED BY THE CONTROLLER, EXTERNAL TAX ACCOUNTANT, AND CFO. AFTER ALL ADJUSTMENTS ARE MADE, THE DRAFT IS REVIEWED WITH THE PRESIDENT. THE FINAL DRAFT OF THE FORM 990 IS THEN REVIEWED WITH THE AUDIT COMMITTEE. THE INSTITUTE THEN POSTS A COPY TO THE BOARD'S WEBSITE AND NOTIFIES MEMBERS OF ITS AVAILABILITY FOR THEIR INFORMATION PRIOR TO SUBMISSION. FORM 990, PART VI, SECTION B, LINE 12C COVERED PERSONS ARE REQUESTED TO SUBMIT ANNUAL DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST FORMS WHICH ARE REVIEWED BY MANAGEMENT. COVERED PERSONS INCLUDE THE WISTAR INSTITUTE'S TRUSTEES, OFFICERS, "KEY EMPLOYEES", AND THE NEXT 5 HIGHLY COMPENSATED EMPLOYEES. AS DESCRIBED IN THE DISCLOSURE OF CONFLICT OF INTEREST POLICY, IF AN INDIVIDUAL HAS ANY POWER OR INFLUENCE TO APPROVE OR DISAPPROVE A CONTRACT OR TRANSACTION PROPOSED TO BE ENTERED INTO BETWEEN THE INSTITUTE AND ANY ENTITY OR PERSON HAVE A SIGNIFICANT RELATIONSHIP TO THAT INDIVIDUAL, THAT INDIVIDUAL HAS A POTENTIAL CONFLICT OF INTEREST AND MAY NOT PARTICIPATE IN THE PROCESS LEADING TO THE APPROVAL OR DISAPPROVAL OF THE CONTRACT OR TRANSACTION UNLESS UNDERLYING FACTS GIVING RISE TO THE POTENTIAL CONFLICT OF INTEREST ARE DISCLOSED AND APPROVAL FOR PARTICIPATION IS OBTAINED. IN THE CASE OF THE BOARD OF TRUSTEES, NO INDIVIDUAL WITH A POTENTIAL CONFLICT OF INTEREST WITH RESPECT TO A CONTRACT OR TRANSACTION OR ANY OTHER CONFLICT OF INTEREST MAY VOTE TO APPROVE OR DISAPPROVE THE CONTRACT OR TRANSACTION. FORM 990, PART VI, SECTION B, LINE 15 THE BOARD OF TRUSTEES HAS DELEGATED AUTHORITY TO OVERSEE THE COMPENSATION PAID TO THE ORGANIZATION'S EXECUTIVES TO THE EXECUTIVE EVALUATION AND COMPENSATION COMMITTEE MADE UP EXCLUSIVELY OF INDEPENDENT MEMBERS OF THE BOARD OF TRUSTEES. THE COMMITTEE FOLLOWS THE PROCEDURES SET FORTH IN THE IRS REGULATIONS UNDER SECTION 4958 IN MAKING COMPENSATION DECISIONS. IN PARTICULAR, THE COMMITTEE ANNUALLY CONDUCTS A REVIEW OF EXECUTIVE COMPENSATION BASED ON INDEPENDENT COMPENSATION SURVEY INFORMATION. AT LEAST EVERY OTHER YEAR, THE COMMITTEE ENGAGES AN INDEPENDENT CONSULTANT TO COLLECT COMPARATIVE COMPENSATION DATA AND PROVIDE A WRITTEN OPINION ON THE REASONABLENESS OF THE PROPOSED COMPENSATION FOR EXECUTIVES. THE COMMITTEE DOCUMENTED ITS COMPENSATION DECISION IN CONTEMPORANEOUS WRITTEN MINUTES. FORM 990, PART VI, SECTION C, LINE 19 THE INSTITUTE'S GOVERNING DOCUMENTS AND CONFLICT OF INTEREST POLICY ARE AVAILABLE ON THE INSTITUTE'S WEBSITE (WWW.WISTAR.ORG). THE INSTITUTE'S FINANCIAL STATEMENTS ARE AVAILABLE UPON REQUEST. FORM 990, PART XI, LINE 9: GAIN ON SPLIT-INTEREST AGREEMENTS 1,725,000. CHANGE IN CASH SURRENDER VALUE OF LIFE INSURANCE POLICIES 6,000. PENSION - NET GAIN 244,000. INTEREST RATE SWAP - NET LOSS -568,000. ISAAC J WISTAR FOUNDATION 3601 SPRUCE STREET PHILADELPHIA PA 19104 232593436 INACTIVE PA 501(C)(3) PF N/A 0 TALL CELL TECHNOLOGY LP C/O THE CONNELLY FDN ONE TOWER BRID WEST CONSHOHOCKEN PA 19428 232811246 LICENSING PA THE WISTAR INSTITUTE OF ANATOMY AND BIOLOGY EXCLUDED 148000 18000 0 1 0.90000 BENEFICIAL INTEREST IN CHARITABLE REMAINDER TRUST PNC WEALTH MANAGEMENT 620 LIBERTY AVE PITTSBURGH PA 15222 TRUST PA PNC BANK T -58000 201000 1.00000 0 BENEFICIAL INTEREST IN PERPETUAL TRUSTS BNY MELLON WEALTH MANAGEMENT 1735 MARKET STREET PHILADELPHIA PA 19103 TRUSTS PA BNY MELLON BANK T 1599000 16998000 1.00000 0 BENEFICIAL INTEREST IN PERPETUAL TRUSTS PNC INSTITUTIONAL INVESTMENTS 620 LIBERTY AVE PITTSBURGH PA 15222 TRUSTS PA PNC BANK T 167000 1906000 1.00000 0 1 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 TALL CELL TECHNOLOGY LP A 148000 COST