2023-11-14T11:22:12-06:00 2022-12-31 135565207 KPMG LLP 60 SOUTH STREET TWO FINANCIAL CENTER BOSTON MA 02111 990 2022-01-01 010211513 THE JACKSON LABORATORY JACK 2072886000 600 MAIN STREET BAR HARBOR ME 04609 DOUGLAS ABBOTT CFO 2072886000 2023-11-13 1 DOUGLAS ABBOTT XXX-XX-XXXX 0 KARA GOODSELL P01783625 6179881000 2023-11-10 2 AAL1 IAL1 2022 2023-04-26 12:10:37Z LON CARDON 600 MAIN STREET BAR HARBOR ME 04609 660081851 0 X WWW.JAX.ORG X 1929 ME THE PURPOSES OF THE LABORATORY ARE SCIENTIFIC, MEDICAL, CHARITABLE, AND EDUCATIONAL. OUR MISSION IS TO DISCOVER PRECISE GENOMIC SOLUTIONS FOR DISEASE AND EMPOWER THE BIOMEDICAL COMMUNITY. 28 27 3166 27 1950277 495392 120757756 119479687 415233744 416727477 34968069 16680856 1914826 627550 572874395 553515570 2892537 2773594 0 0 266577106 291592343 0 0 3910720 240025612 238449779 509495255 532815716 63379140 20699854 1458479631 1394651570 448097405 442780639 1010382226 951870931 X SEE SCHEDULE O 0 1 283996222 170417 415664580 DEVELOP AND PROVIDE GENETIC RESOURCESTHE JACKSON LABORATORY (JAX) IS A GLOBAL RESOURCE FOR DEVELOPING, DISTRIBUTING AND ANALYZING INNOVATIVE MODELS OF HUMAN DISEASE. IT OFFERS AN ARRAY OF MODEL CREATION, HUSBANDRY AND DIAGNOSTIC AND ANALYTICAL SERVICES, RANGING FROM CUSTOM BREEDING AND STRAIN PRESERVATION TO DRUG EFFICACY STUDIES AND GENOME SEQUENCING, ALL FOCUSED ON EMPOWERING BASIC SCIENTIFIC RESEARCH AND DRUG DISCOVERY.JAX MAINTAINS CLOSE TO 13,000 GENETICALLY DISTINCT STRAINS OF RESEARCH MICE. IN 2022, DISTRIBUTED THEM TO RESEARCHERS FROM MORE THAN 2,400 ORGANIZATIONS, IN UPWARDS OF 68 COUNTRIES USED JAX RESEARCH MICE TO SUPPORT EFFORTS TO FIND CURES FOR THE WORLD'S MOST DEVASTATING HUMAN DISEASES AND BRING ADVANCED THERAPIES TO PATIENTS. THE LABORATORY ALSO HOSTS THE MOUSE GENOME INFORMATICS DATABASES, THE WORLD'S SOURCE FOR INFORMATION ON MOUSE GENETICS AND BIOLOGY.IN 2022, 500 MOUSE STRAINS WERE DONATED TO THE LABORATORY OR DEVELOPED BY JAX RESEARCH STAFF WITH ACADEMIC/FOUNDATION OR PUBLICLY FUNDED RESEARCH PROGRAMS. THE LABORATORY MAKES THESE RESOURCES PUBLICLY ACCESSIBLE THROUGH ITS REPOSITORY, PRODUCTION AND RESEARCH SERVICES. DISTRIBUTION OF THESE STRAINS HELPS SUPPORT CURES FOR THE WORLD'S MOST PREVALENT HUMAN DISEASES AND ACCELERATES THE TIME TO BRING NEW THERAPIES TO PATIENTS. THE LABORATORY COLLABORATED WITH OTHER NON-PROFIT PATIENT FOUNDATIONS FOR RARE DISEASES TO ESTABLISH MOUSE RESOURCES TO FURTHER PRECLINICAL THERAPEUTIC STUDIES.THE LABORATORY MAKES THE JAX CLINICAL KNOWLEDGEBASE (CKB) RESOURCE PUBLICLY AVAILABLE, ENABLING CLINICIANS, AND TRANSLATIONAL RESEARCHERS TO INTERPRET COMPLEX CANCER GENOMIC PROFILES. ACCEPTANCE AND USAGE OF CKB HAS BEEN STEADILY INCREASING; CKB HAS RECEIVED OVER 900,000 VISITS SINCE ITS LAUNCH IN 2016. THE PUBLIC SITE HAD OVER 3,000,000 PAGE VIEWS IN THAT PERIOD. 163634057 1334617 494677 BIOMEDICAL RESEARCHTHE LABORATORY'S RESEARCHERS COMBINE EXPERIENCE IN MAMMALIAN GENETICS AND HUMAN GENOMICS TO SHAPE AN INTEGRATED APPROACH TO PERSONALIZED MEDICINE. SCIENTISTS WORK COLLABORATIVELY AND CROSS-DISCIPLINE, LEVERAGING EXPERTISE IN CANCER, IMMUNOLOGY, NEUROGENETICS, LIFE-CYCLE BIOLOGY, THE MICROBIOME, AND COMPUTATIONAL BIOLOGY.MORE THAN 400 JAX STAFF MEMBERS HOLD ADVANCED DEGREES AND THE LABORATORY SUPPORTS MORE THAN 60 RESEARCH TEAMS. FACULTY MEMBERS HAVE 324 ACTIVE SPONSORED RESEARCH COLLABORATION AGREEMENTS WITH 245 ACADEMIC RESEARCH AND CLINICAL INSTITUTIONS. MULTIPLE LABORATORY CENTERS COORDINATE EXPERTISE AROUND CRITICAL RESEARCH AREAS. SINCE 1983 THE LABORATORY HAS HAD A NATIONAL CANCER INSTITUTE-DESIGNATED CANCER CENTER, ONE OF ONLY SEVEN SUCH DESIGNATED INSTITUTIONS IN THE UNITED STATES. TO DATE 26 NOBEL PRIZES ARE ASSOCIATED WITH LABORATORY RESEARCH, EDUCATION PROGRAMS AND RESOURCES. 10731581 1268560 568220 EDUCATION AND TRAININGTHE LABORATORY OFFERS EDUCATIONAL PROGRAMS FOR SCIENTISTS THROUGHOUT THEIR CAREERS FROM STEM EDUCATION FOR HIGH SCHOOL STUDENTS AND TRAINING FOR SCIENCE AND MATH TEACHERS TO COURSES AND CONFERENCES FOR EXPERIENCED RESEARCHERS DEFINING THE CUTTING EDGE OF GENOMICS INTO THEIR PRACTICES.FOR MORE INFORMATION ON THE LABORATORY'S PROGRAM SERVICES, PLEASE REFER TO THE JACKSON LABORATORY 2022 ACCOMPLISHMENTS AT HTTPS://WWW.JAX.ORG/NEWS-AND-INSIGHTS/2022/DECEMBER/2022-MOMENTUM-PRESS-RELEASE. 711281 INVESTMENT INCOME/ROYALTIES/REALIZED GAINS 711281 458361860 1 1 0 1 0 0 0 1 0 1 1 1 0 1 1 1 0 1 0 1 1 0 0 0 0 0 0 1 1 1 0 0 0 0 0 0 1 0 1 0 0 0 1 1 1 1 0 0 1 349 0 1 3166 1 1 1 1 CH HK JA 0 0 0 0 0 0 0 0 1 0 X 28 27 0 0 1 0 0 0 0 1 1 0 0 1 1 1 1 1 1 1 1 1 1 CA CT FL GA IL MA ME MI MS NC ND NH NJ NM NY OH OK OR PA RI SC VA WA WI WV X X X DOUGLAS ABBOTT 2072886045 600 MAIN STREET BAR HARBOR ME 04609 DAVID J ROUX CHAIR EMERITUS 2.00 X 0 0 0 THOMAS C BARRY TRUSTEE 2.00 X 0 0 0 OTIS W BRAWLEY MD TRUSTEE 2.00 X 0 0 0 TIMOTHY D DATTELS BOARD CHAIR 5.00 X X 0 0 0 JULIE H DAUM TRUSTEE 2.00 X 0 0 0 LON CARDON PHD FMEDSCI PRESIDENT & CEO 40.00 X X 1299235 0 197226 STEVEN B FINK JD TRUSTEE 2.00 X 0 0 0 JEFFREY M FRIEDMAN MD PHD TRUSTEE 2.00 X 0 0 0 JEAN HOFFMAN UNTIL 1222 TRUSTEE 2.00 X 0 0 0 JOHN A GIBBONS JR TRUSTEE 2.00 X 0 0 0 NEAL B MILCH JD VICE CHAIR 2.00 X 0 0 0 GEORGE G MONTGOMERY TRUSTEE 2.00 X 0 0 0 FRANK MOSS PHD TRUSTEE 2.00 X 0 0 0 DENNIS J PAUSTENBACH PHD TRUSTEE 2.00 X 0 0 0 JENNY E ROOKE PHD TRUSTEE 2.00 X 0 0 0 JOSHUA BRODER TRUSTEE 2.00 X 0 0 0 MARY KATE WOLD JD TRUSTEE 2.00 X 0 0 0 GEOFFREY W SMITH JD TRUSTEE 2.00 X 0 0 0 JOAN A STEITZ PHD TRUSTEE 2.00 X 0 0 0 CHARLES E HEWETT PHD TRUSTEE 2.00 X 0 0 0 BERTRAND GARCIA-MORENO PHD TRUSTEE 2.00 X 0 0 0 ADAORA A ADIMORA MD MPH TRUSTEE 2.00 X 0 0 0 CARLA E BRODLEY PHD VICE CHAIR 2.00 X 0 0 0 JOHN LOWRY TRUSTEE 2.00 X 0 0 0 MELISSA C GUZY TRUSTEE 2.00 X 0 0 0 JOHN SCHIMENTI PHD UNTIL 822 TRUSTEE 2.00 X 0 0 0 SANDRA WAITE JD TRUSTEE 2.00 X 0 0 0 NANCY J COX PHD TRUSTEE 2.00 X 0 0 0 JANET ROSSANT PHD TRUSTEE 2.00 X 0 0 0 DINAKAR SINGH TRUSTEE 2.00 X 0 0 0 S CATHERINE LONGLEY EXECUTIVE VICE PRESIDENT & COO 40.00 X 938613 0 114261 DOUGLAS ABBOTT SR VICE PRESIDENT & CFO 40.00 X 507735 0 111435 DANIEL HOAG GENERAL COUNSEL & SECRETARY 40.00 X 506599 0 59808 AUROBINDO NAIR UNTIL 922 EXECUTIVE VP & PRESIDENT JMCRS 40.00 X 1019881 0 50708 KENNETH FASMAN UNTIL 1022 SENIOR VICE PRESIDENT RESEARCH 40.00 X 605025 0 57829 NADIA A ROSENTHAL SCIENTIFIC DIRECTOR 40.00 X 537543 0 30952 CHARLES LEE MD SCIENTIFIC DIRECTOR, JAX GM 40.00 X 494739 0 61185 EDISON T LIU MD FORMER PRESIDENT & CEO 40.00 X 1336777 0 52110 JENS RUETER MEDICAL DIRECTOR 40.00 X 495496 0 61919 BARBARA-JEAN BORMANN-KENNEDY VP SCI TRANSLATION/ALLIANCES 40.00 X 479169 0 30946 CHARLES MILLER VP, JMCRS ASIA PACIFIC MARKET 40.00 X 488329 90000 66172 DAVID GRASS VP, JMCRS MICE & SERVICES OPS 40.00 X 477771 0 61164 9186912 90000 955715 509 1 1 0 WHITING TURNER CONTRACTING 300 EAST JOPPA ROAD BALTIMORE MD 21286 CONSTRUCTION MGMT 19326058 BIOTRANS LLC 9 LIDGERWOOD PLACE MORRISTOWN NJ 07960 TRANSPORTATION 9663447 TLR VENTURES INC 2719 SEQUOIA WAY BELMONT CA 94002 CONSULTING SERVICES 8306681 LANDRYFRENCH CONSTRUCTION CO 160 PLEASANT HILL ROAD SCARBOROUGH ME 04074 CONSTRUCTION MGMT 7938576 MARKETONE BUILDERS INC 1200 R ST STE 150 SACRAMENTO CA 95811 CONSTRUCTION MGMT 5272466 162 101815474 17664213 2252268 119479687 GENETIC RESOURCES 541700 415664580 415037659 626921 TRAINING & EDUCATION 541700 568220 568220 RESEARCH 541700 494677 494677 416727477 14188030 1323356 12864674 41223 41223 206666 331620 -124954 -124954 -124954 108690487 37000 105337698 896963 3352789 -859963 2492826 2492826 INTERCOMPANY REVENUE 818447 818447 OTHER REVENUE 337789 337789 FOREIGN EXCHANGE LOSS -444955 -444955 711281 553515570 416811837 1950277 15273769 298065 298065 2475529 2475529 6353401 2012609 4340792 214903818 183640082 28792738 2470998 18100553 15766729 2122905 210919 36955741 29480635 7083700 391406 15278830 13056100 2047052 175678 3092293 3092293 425770 425770 365320 365320 29953169 23418142 6379425 155602 1855716 1579702 275014 1000 1335716 839260 472462 23994 20711985 16024421 4542990 144574 3203161 3203161 17445803 16247536 1198267 6916206 4824283 1888294 203629 123899 103631 20057 211 7683570 7414542 269028 52261314 49366026 2895288 3221609 3123732 97877 SUPPLIES 81429453 78476015 2832076 121362 OTHER SERVICES 4957265 3453814 1499120 4331 INTERCO SERVICE FEE 1854092 1854092 EQUIPMENT RENTAL 1253733 1169378 77339 7016 359705 534376 -174671 532815716 458361860 70543136 3910720 277847895 244777217 13889936 18515968 82948141 45044565 11892387 11879627 10488945 12620335 1132100915 520898029 557032415 611202886 332258387 239013777 113377340 137155605 58744185 74441590 1458479631 1394651570 81419513 83582083 14872726 14109251 351805166 345089305 448097405 442780639 X 907368411 862307249 103013815 89563682 1010382226 951870931 1458479631 1394651570 20699854 -82812987 3601838 0 X 0 1 X 1 1 1 X 111234633 131073861 122912211 120757756 119479687 605458148 111234633 131073861 122912211 120757756 119479687 605458148 17831839 587626309 18347382 13604379 10487014 16312028 14435919 73186722 475189 339977 479786 293179 496671 2084802 9031603 344223 121238 1640811 711281 11849156 692578828 1798997074 0.84850 0.82280 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED 0 1 0 0 0 0 1 207970 0 0 207970 0 FORM 990, SCH. C, PART II-B, LINE 1G LOBBYING ACTIVITY BY NON-ELECTING 501(C)(3) ORGANIZATION THE TOTAL LOBBYING EXPENSE FOR THE YEAR ENDED DECEMBER 31, 2022 WAS $207,970, WHICH IS AN ALLOCATION OF EMPLOYEE COMPENSATION FOR LOBBYING ACTIVITIES. 601346 X 0 445636754 2931591 -61281789 159911 10957266 376169382 386957560 6864818 61288861 9474485 445636754 306403790 32802634 55001080 7249944 386957560 261889680 3045938 46408311 166468 4773671 306403790 167681269 115378127 -16079673 147601 4942442 261889680 0.77830 0.13490 0.08680 0 0 14265669 14265669 770542439 341090520 429451919 231907220 179807509 52099711 115385587 115385587 611202886 ALTERNATIVE 137155605 F 137155605 ME DOL UNEMPLOYMENT BOND CD 1053750 OTHER 57368987 EMPLOYEE BENEFIT ASSETS 16018853 74441590 RETIREMENT PLAN OBLIGATIONS 5122441 BONDS 339966864 345089305 X 478450714 -82812987 7416511 -75396476 553847190 -331620 -331620 553515570 575372381 47898071 47898071 527474310 5341406 5341406 532815716 PART III, LINE 4: CERTAIN DONORS CONTRIBUTE WORKS OF ART IN LIEU OF CASH CONTRIBUTIONS. THE LABORATORY HAS UNDERTAKEN TO HOLD THE ITEMS FOR PRESERVATION FOR FUTURE GENERATIONS. PART V, LINE 4: THE INVESTMENT AND SPENDING POLICIES FOR THE ENDOWMENT ASSETS HAVE BEEN ESTABLISHED TO PROVIDE A PREDICTABLE STREAM OF FUNDING FOR THE PROGRAMS SUPPORTED BY THE ENDOWMENT WHILE SEEKING TO MAINTAIN THE PURCHASING POWER OF THE ENDOWMENT ASSETS. ENDOWMENT FUNDS WERE PRIMARILY SPENT ON RESEARCH, TRAINING AND EDUCATION. PART X, LINE 2: THE LABORATORY IS A NOT-FOR-PROFIT ORGANIZATION AS DESCRIBED IN SECTION 501(C)(3) OF THE INTERNAL REVENUE CODE (THE CODE), AS AMENDED, AND IS GENERALLY EXEMPT FROM INCOME TAXES PURSUANT TO THE CODE. JAX SHANGHAI AND JAX BEIJING ARE TAXABLE ENTITIES ORGANIZED UNDER THE REGULATIONS OF THE PEOPLE'S REPUBLIC OF CHINA. JAX HONG KONG IS A TAXABLE ENTITY ORGANIZED UNDER THE REGULATIONS OF HONG KONG. JAX JAPAN HOLDINGS AND JAX JAPAN ARE TAXABLE ENTITIES ORGANIZED UNDER THE REGULATIONS OF JAPAN. IN ACCORDANCE WITH GAAP, THE LABORATORY ASSESSES WHETHER THERE ARE UNCERTAIN TAX POSITIONS AND DETERMINED THAT THERE WERE NO UNCERTAIN TAX POSITIONS THAT WOULD HAVE A MATERIAL EFFECT ON THE CONSOLIDATED FINANCIAL STATEMENTS. PART XI, LINE 2D - OTHER ADJUSTMENTS: FOREIGN SUBSIDIARY NOT REPORTED ON 990 11,660,599. NON-OPERATING EXPENSES -4,244,088. PART XI, LINE 4B - OTHER ADJUSTMENTS: RENTAL EXPENSES -331,620. PART XII, LINE 2D - OTHER ADJUSTMENTS: FOREIGN SUBSIDIARY NOT REPORTED ON 990 47,566,451. RENTAL EXPENSES 331,620. PART XII, LINE 4B - OTHER ADJUSTMENTS: NON-OPERATING EXPENSES 5,341,406. CENTRAL AMERICA AND THE CARIBBEAN INVESTMENTS 24568086 EUROPE (INCLUDING ICELAND AND GREENLAND) PROGRAM SERVICES GENETIC RESOURCES MIDDLE EAST AND NORTH AFRICA PROGRAM SERVICES GENETIC RESOURCES NORTH AMERICA PROGRAM SERVICES GENETIC RESOURCES SOUTH AMERICA PROGRAM SERVICES GENETIC RESOURCES SOUTH ASIA PROGRAM SERVICES GENETIC RESOURCES 97097 EAST ASIA AND THE PACIFIC PROGRAM SERVICES RESEARCH RUSSIA AND THE NEWLY INDEPENDENT STATES PROGRAM SERVICES GENETIC RESOURCES SUB-SAHARAN AFRICA PROGRAM SERVICES GENETIC RESOURCES EAST ASIA AND THE PACIFIC PROGRAM SERVICES GENETIC RESOURCES 331771 EUROPE (INCLUDING ICELAND AND GREENLAND) 5 PROGRAM SERVICES GENETIC RESOURCES 853547 0 0 0 5 0 5 24665183 1185318 25850501 1 0 1 1 1 1 PART III ACCOUNTING METHOD: FORM 990, SCH. F, PART I, LINE 3, COLUMN F THE BASIS OF ACCOUNTING ON THE FINANCIAL STATEMENTS IS ACCRUAL. 1 TOWN OF BAR HARBOR 49 PARK STREET BAR HARBOR ME 04609 016000061 GOV'T 115781 0 FMV N/A GENERAL SUPPORT CITY OF ELLSWORTH 1 CITY HALL PLAZA ELLSWORTH ME 04605 016000027 GOV'T 54636 0 FMV N/A GENERAL SUPPORT CONNECTICUT SCIENCE CENTER INC 250 COLUMBUS BLVD HARTFORD CT 06103 061538101 501(C)(3) 25533 0 FMV N/A GENERAL SUPPORT SACRAMENTO POLICE FOUNDATION 5960 S LAND PARK DR SACRAMENTO CA 95822 680433279 501(C)(3) 7000 0 FMV N/A GENERAL SUPPORT JESUP MEMORIAL LIBRARY 34 MOUNT DESERT STREET BAR HARBOR ME 04609 010214017 501(C)(3) 7500 0 FMV N/A GENERAL SUPPORT MOUNT DESERT ISLAND YMCA 21 PARK STREET BAR HARBOR ME 04609 010211486 501(C)(3) 6000 0 FMV N/A GENERAL SUPPORT NATIONAL ACADEMIES OF SCIENCE ENGINEERING MEDICINE 2101 CONSITUTION AVENUE B WASHINGTON DC 20418 530196932 501(C)(3) 12000 0 FMV N/A GENERAL SUPPORT TRANSLATIONAL RESEARCH CANCER CENTER CONSORTIUM IN 1227 SOUTH BRADDOCK AVE PITTSBURGH PA 15218 831794049 501(C)(3) 7500 0 FMV N/A GENERAL SUPPORT CENTRAL CONNECTICUT STATE UNIVERSITY 1615 STANLEY STREET NEW BRITAIN CT 06053 061303381 GOV'T 0 14000 BOOK LAB TESTING SUPPLIES LABORATORY TESTING SUPPLIES NORTHWESTERN UNIVERSITY 633 CLARK STREET EVANSTON IL 60208 362167817 501(C)(3) 0 14000 BOOK LAB TESTING SUPPLIES LABORATORY TESTING SUPPLIES CONNECTICUT OFFICE OF THE CHIEF MEDICAL EXAMINER 11 SHUTTLE RD FARMINGTON CT 06032 066000798 GOV'T 0 14000 BOOK LAB TESTING SUPPLIES LABORATORY TESTING SUPPLIES ALZHEIMER'S ASSOCIATION 225 N MICHIGAN AVE 17TH FL CHICAGO IL 60601 133039601 501(C)(3) 7000 0 FMV N/A GENERAL SUPPORT HUMAN GENOME ORGANIZATION 10 DISCOVERY DRIVE FARMINGTON CT 06032 853902726 501(C)(3) 14760 0 FMV N/A GENERAL SUPPORT 13 SCHOLARSHIPS/STIPENDS 1060 2475529 FMV N/A SCHEDULE I, PART II, 1(A) IN RECOGNITION OF THE CLOSE RELATIONSHIP BETWEEN THE LABORATORY AND THE TOWN OF BAR HARBOR, THE LABORATORY MADE A VOLUNTARY PAYMENT TO THE TOWN. IN RECOGNITION OF THE CLOSE RELATIONSHIP BETWEEN THE LABORATORY AND THE CITY OF ELLSWORTH, THE LABORATORY MADE A VOLUNTARY PAYMENT TO THE CITY. THE MISSION OF THE CONNECTICUT SCIENCE CENTER TO INSPIRE LIFE-LONG LEARNING THROUGH THE OPERATION OF A SCIENCE CENTER IS CLOSELY ALIGNED WITH THE ORGANIZATION'S EDUCATIONAL MISSION. IN RECOGNITION OF THE CLOSE RELATIONSHIP BETWEEN THE LABORATORY AND THE SACRAMENTO POLICE DEPARTMENT, THE LABORATORY MADE A VOLUNTARY PAYMENT TO THE SACRAMENTO POLICE FOUNDATION. IN RECOGNITION OF THE IMPORTANCE OF THE PUBLIC LIBRARY AND MEETING PLACE TO THE COMMUNITY, THE LABORATORY MADE A VOLUNTARY PAYMENT TO THE JESUP MEMORIAL LIBRARY. IN RECOGNITION OF THE IMPORTANCE OF THE YMCA IN DEVELOPING COMMUNITY, CHARACTER, PERSONAL GROWTH AND WELLNESS, THE LABORATORY MADE A VOLUNTARY PAYMENT TO THE MOUNT DESERT ISLAND YMCA. THE MISSION OF THE NATIONAL ACADEMIES OF SCIENCES, ENGINEERING AND MEDICINE DEDICATED TO THE FURTHERANCE OF SCIENCE AND ITS USE FOR THE GENERAL WELFARE IS CLOSELY ALIGNED WITH THE ORGANIZATION'S RESEARCH MISSION. THE MISSION OF THE TRANSLATIONAL RESEARCH CANCER CENTERS CONSORTIUM IS TO GAIN A GREATER UNDERSTANDING OF THE INTERACTIONS BETWEEN THE IMMUNE SYSTEM AND CANCER IN THE SETTING OF BIOLOGIC THERAPY OF CANCER. THIS IS CLOSELY ALIGNED WITH THE LABORATORY'S RESEARCH MISSION. THE LABORATORY MADE DONATIONS OF EXCESS LABORATORY TESTING SUPPLIES TO CENTRAL CONNECTICUT STATE UNIVERSITY, NORTHWESTERN UNIVERSITY AND THE CONNECTICUT OFFICE OF THE CHIEF MEDICAL EXAMINER. THESE WERE SUPPLIES THAT WERE NO LONGER BEING USED AND WAS DONATED TO OTHER NONPROFIT AND GOVERNMENT ORGANIZATIONS THAT COULD USE THEM. THE ALLOCATION OF GRANTS AND OTHER ASSISTANCE TO LOCAL ORGANIZATIONS IS DETERMINED ON AN ANNUAL BASIS. VARYING AMOUNTS OF ASSISTANCE IN THE FORM OF GRANTS, FELLOWSHIPS AND STIPENDS ARE AWARDED TO SUMMER STUDENTS, LABORATORY INTERNS, GRADUATE STUDENTS, INSTRUCTORS AND COURSE ATTENDEES BASED ON NEED AND MERIT. ALL RECIPIENTS OF STIPENDS AND SCHOLARSHIPS EITHER WORK AT THE LABORATORY UNDER THE SUPERVISION OF LABORATORY EMPLOYEES OR ATTEND COURSES. CONFERENCE ORGANIZERS REGULARLY MONITOR ATTENDANCE OF COURSES BY GRANT RECIPIENTS, AND RESPONSIBLE FACULTY MEMBERS OVERSEE AND MONITOR OTHER FORMS OF SCHOLARSHIP ASSISTANCE TO INDIVIDUAL STUDENTS, INTERNS OR OTHER SCIENTISTS THROUGH OVERSIGHT OF THEIR ASSIGNMENTS. THE LABORATORY GRANTS SCHOLARSHIPS TO A SELECT NUMBER OF HIGH SCHOOL STUDENTS ON AN ANNUAL BASIS. SCHEDULE I, PART II X X 1 1 X X X X X 0 1 0 0 0 0 0 1 0 LON CARDON PHD FMEDSCI PRESIDENT & CEO 1100002 0 0 0 199233 0 165000 0 32226 0 1496461 0 0 0 EDISON T LIU MD FORMER PRESIDENT & CEO 451920 0 250000 0 634857 0 29343 0 22767 0 1388887 0 0 0 AUROBINDO NAIR UNTIL 922 EXECUTIVE VP & PRESIDENT JMCRS 696662 0 309310 0 13909 0 29750 0 20958 0 1070589 0 0 0 S CATHERINE LONGLEY EXECUTIVE VICE PRESIDENT & COO 580329 0 242920 0 115364 0 100500 0 13761 0 1052874 0 0 0 KENNETH FASMAN UNTIL 1022 SENIOR VICE PRESIDENT RESEARCH 456791 0 145218 0 3016 0 30500 0 27329 0 662854 0 0 0 CHARLES MILLER VP, JMCRS ASIA PACIFIC MARKET 272298 90000 90000 0 126031 0 27230 0 38942 0 554501 90000 0 0 DOUGLAS ABBOTT SR VICE PRESIDENT & CFO 414764 0 91511 0 1460 0 80500 0 30935 0 619170 0 0 0 NADIA A ROSENTHAL SCIENTIFIC DIRECTOR 453263 0 76772 0 7508 0 30500 0 452 0 568495 0 0 0 DANIEL HOAG GENERAL COUNSEL & SECRETARY 416325 0 56382 0 33892 0 15250 0 44558 0 566407 0 0 0 JENS RUETER MEDICAL DIRECTOR 411954 0 81000 0 2542 0 30500 0 31419 0 557415 0 0 0 CHARLES LEE MD SCIENTIFIC DIRECTOR, JAX GM 424551 0 68296 0 1892 0 30500 0 30685 0 555924 0 0 0 DAVID GRASS VP, JMCRS MICE & SERVICES OPS 350491 0 93077 0 34203 0 28124 0 33040 0 538935 0 0 0 BARBARA-JEAN BORMANN-KENNEDY VP SCI TRANSLATION/ALLIANCES 381388 0 78567 0 19214 0 30500 0 446 0 510115 0 0 0 PART I, LINE 1A TAX INDEMNIFICATION AND GROSS-UP PAYMENTS: THE JACKSON LABORATORY GROSSES UP THE AMOUNT ADDED TO WAGES FOR IMPUTED INSURANCE PREMIUMS FOR LIFE, DISABILITY, AND LONG TERM CARE BENEFITS FOR THE SENIOR MANAGEMENT GROUP TO COVER TAXES. THE LABORATORY ALSO GROSSES UP WAGES TO COVER THE TAX IMPACT OF GIFT CARDS AND OTHER AWARDS OR PRIZES TO EMPLOYEES SO THAT THE RECIPIENTS RECEIVE THE FULL VALUE OF THE GIFT OR AWARD. HOUSING ALLOWANCE OR RESIDENCE FOR PERSONAL USE: THE LABORATORY PROVIDES A HOUSING ALLOWANCE TO THE PRESIDENT. THE AMOUNT IS INCLUDED IN SCHEDULE J, PART II, COLUMN (B)(III). PART I, LINE 4B THE LABORATORY MAINTAINS A DEFERRED COMPENSATION PLAN UNDER SECTION 457(F): CONTRIBUTIONS MADE: PRESIDENT/CEO $165,000 EXECUTIVE VICE PRESIDENT/COO $70,000 SR VP & CHIEF FINANCIAL OFFICER $50,000 SR VP & CHIEF HUMAN RES OFFICE $15,831 GENERAL COUNSEL $6,922 DISTRIBUTIONS MADE: FORMER PRESIDENT/CEO $556,407 PART I, LINE 7 THE TOTAL COMPENSATION PACKAGE OF CERTAIN OFFICERS, KEY EMPLOYEES, AND OTHER EMPLOYEES INCLUDES VARIABLE COMPENSATION AWARDED BASED ON PERFORMANCE. ALAN SAWYER KEY EMPLOYEE -N ROSENTHAL 269426 EMPLOYMENT - FAMILY MEMBER 0 X 20 2252268 FMV 0 1 0 FORM 990, SCH. M, PART I, COLUMN B CONTRIBUTIONS THE NUMBER OF CONTRIBUTIONS ARE REPORTED IN COLUMN B. FORM 990, PART III, LINE 3 AS PART OF OUR MISSION TO IMPROVE HUMAN HEALTH, IN EARLY 2020 JAX BEGAN TESTING HUMAN SPECIMENS FOR THE VIRUS THAT CAUSES COVID-19. THIS TESTING CEASED DURING 2022. FORM 990, PART III, LINE 1 THE PURPOSES OF THE LABORATORY ARE SCIENTIFIC, MEDICAL, CHARITABLE, AND EDUCATIONAL TO DISCOVER PRECISE GENOMIC SOLUTIONS FOR DISEASE AND EMPOWER THE BIOMEDICAL COMMUNITY. TO ACCOMPLISH THIS MISSION, THE LABORATORY: 1) CONDUCTS BASIC BIOMEDICAL RESEARCH TO INCREASE THE KNOWLEDGE OF DEVELOPMENT, GROWTH, REPRODUCTION, PHYSIOLOGY, AND PATHOPHYSIOLOGY THROUGH RESEARCH WITH GENETICALLY DEFINED EXPERIMENTAL MOUSE MODELS AND OTHER MODELS OF DISEASE; 2) CONDUCTS TRANSLATIONAL BIOMEDICAL RESEARCH TO IDENTIFY THE GENOMIC IMPACT ON HUMAN DISEASE, PROMOTE THE ESTABLISHMENT OF MORE PRECISE, TARGETED THERAPIES, OFFER CUTTING EDGE GENOMIC DIAGNOSTICS TO IMPROVE PATIENT CARE, AND PROVIDE ADVANCED COMPUTATIONAL TOOLS, DATABASES AND KNOWLEDGE MANAGEMENT SYSTEMS TO THE BIOMEDICAL RESEARCH AND MEDICAL COMMUNITIES; 3) TRAINS AND EDUCATES STUDENTS, SCIENTISTS, PHYSICIANS, AND OTHER PROFESSIONALS IN THESE AREAS; AND 4) PROMOTES SCIENTIFIC DISCOVERY THROUGH THE PROVISION OF MOUSE MODELS AND OTHER MODELS OF HUMAN DISEASE AND THE PROVISION OF RESEARCH, CLINICAL, COMPUTATIONAL AND INFORMATION SERVICES TO THE GLOBAL SCIENTIFIC AND MEDICAL COMMUNITIES. FORM 990, PART VI, SECTION A, LINE 4 THE CORPORATE BYLAWS WERE AMENDED ON DECEMBER 7, 2022 TO ADD THE SCIENCE AND TECHNOLOGY COMMITTEE TO THE PERMANENT STANDING COMMITTEES OF THE BOARD OF TRUSTEES. ADOPTION OF THE ANNUAL OPERATING, CAPITAL BUDGETS, AND APPROPRIATION AND ALLOCATION OF ENDOWMENT INCOME OF THE LABORATORY WAS ALSO ADDED AS ACTIONS RESERVED TO THE FULL BOARD. APPROVAL AND OVERSIGHT OF CAPITAL EXPENDITURES, APPROVAL AND OVERSIGHT OF OPERATING AND CAPITAL EXPENDITURE UNBUDGETED ITEMS THAT EXCEED A RESOLUTION APPROVED MONETARY THRESHOLD WAS ADDED TO THE FINANCE COMMITTEE'S RESPONSIBILITIES. FORM 990, PART VI, SECTION B, LINE 11B FORM 990 REVIEW PROCESS THE AUDIT AND ENTERPRISE RISK MANAGEMENT COMMITTEE OF THE JACKSON LABORATORY'S BOARD OF TRUSTEES REVIEWS A DRAFT COPY OF THE IRS FORM 990 BEFORE IT IS PROVIDED TO THE BOARD OF TRUSTEES. AFTER THE AUDIT AND ENTERPRISE RISK MANAGEMENT COMMITTEE'S REVIEW, THE IRS FORM 990 IS FINALIZED AND PROVIDED TO THE BOARD OF TRUSTEES PRIOR TO FILING WITH THE INTERNAL REVENUE SERVICE. FORM 990, PART VI, SECTION B, LINE 12C THE JACKSON LABORATORY REQUESTS ALL OFFICERS, BOARD MEMBERS AND KEY EMPLOYEES COMPLETE A "CERTIFICATION OF COMPLIANCE WITH CONFLICT OF INTEREST POLICY AND CODE OF ETHICS" FORM AND A "CONFLICT OF INTEREST DISCLOSURE FORM" QUESTIONNAIRE, AND DISTRIBUTES ALL POLICIES REGARDING THE CONFLICT OF INTEREST AND CODE OF ETHICS. THIS PROCESS IS DONE ANNUALLY. THE DISCLOSURE AND COMPLIANCE ATTESTATIONS ARE RETURNED TO THE GENERAL COUNSEL, WHERE THEY ARE RECORDED AND TALLIED FOR COMPLETENESS. DISCLOSURES, AS WELL AS ANY FOLLOW UP QUESTIONS, ARE ROUTED THROUGH GENERAL COUNSEL, AND IF NECESSARY THE AUDIT AND ENTERPRISE RISK COMMITTEE. TRUSTEES AND EXECUTIVES WITH AN APPARENT OR ACTUAL CONFLICT OF INTEREST RECUSE THEMSELVES FROM DECISION MAKING. FORM 990, PART VI, SECTION B, LINE 15 COMPENSATION POLICY THE COMPENSATION AND HUMAN RESOURCES COMMITTEE OF THE BOARD OF TRUSTEES SETS COMPENSATION AND BENEFITS FOR THE CHIEF EXECUTIVE OFFICER AND THE COMMITTEE REVIEWS THE COMPENSATION AND BENEFITS FOR THE OFFICERS AND CERTAIN KEY EMPLOYEES LISTED IN SCHEDULE J. MEMBERS OF THE COMMITTEE ARE INDEPENDENT TRUSTEES SELECTED BY THE CHAIR OF THE BOARD OF TRUSTEES. THE COMMITTEE IS GUIDED BY COMPENSATION MARKET DATA FOR SIMILAR POSITIONS IN COMPARABLE ORGANIZATIONS. MARKET DATA IS PREPARED FOR THE COMMITTEE BY AN EXTERNAL EXECUTIVE COMPENSATION FIRM WHICH CONSIDERS COMPENSATION INFORMATION REPORTED IN FORM 990'S OF COMPARABLE ORGANIZATIONS AND THE RESULTS OF RECOGNIZED COMPENSATION SURVEYS. THE CHIEF HUMAN RESOURCES OFFICER IS AVAILABLE TO THE COMMITTEE TO PROVIDE ANY OTHER DATA NEEDED. THE CEO AND COO MEETS WITH THE COMMITTEE AT LEAST ANNUALLY TO REVIEW THE COMPENSATION OF THEIR DIRECT REPORTS. THE COMMITTEE'S REVIEW PROCESS AND RESULTS ARE DOCUMENTED IN MINUTES OF THE MEETINGS. FORM 990, PART VI, SECTION C, LINE 19 THE ORGANIZATION'S FORM 990 IS AVAILABLE ON WWW.GUIDESTAR.ORG AND ON THE ORGANIZATION'S PUBLIC WEBSITE WWW.JAX.ORG. THE ORGANIZATION'S FINANCIAL STATEMENTS ARE AVAILABLE AT WWW.JAX.ORG. THE GOVERNING DOCUMENTS AND CONFLICT OF INTEREST POLICY ARE MADE AVAILABLE TO THE PUBLIC UPON REQUEST. 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