2023-05-04T17:25:50-04:00 2022-12-31 474306215 Mullins PC 7625 Wisconsin Avenue Bethesda MD 20814 990 2022-01-01 813557785 RUNX1 Foundation dba RUNX1 Research Program RUNX 1482 E Valley Rd Ste 137 Santa Barbara CA 93108 Katrin Ericson President Exe 8058804105 2023-05-04 true Katrin Ericson XXX-XX-XXXX John Mullins P01429307 2027706371 2023-05-04 0 00 AAL1 IAL1 2022 2023-04-26 12:10:37Z Katrin Ericson 670719 false X www.runx1-fpd.org X 2016 CA See Schedule O. 3 3 6 23 0 0 5335888 670719 0 0 201 0 5336089 670719 1500912 1477750 0 762470 929656 0 214638 345387 473026 2608769 2880432 2727320 -2209713 3085066 807381 249640 181668 2835426 625713 X See Schedule O. false false 635466 375000 Sponsored Research. 2022 Mark Foundation Cancer Research (MFCR) Seeking Transformational Research Venture (STRIVE) - Continued Matching Grant partnership. Sponsoring Institutes include research by Dr. Ravindra Majeti, Stanford University; Dr. Lucy Godley, University of Chicago; and Lucio Castilla, University of Massachusetts Medical School. 618521 365000 Sponsored Research. 2022 co-funding partnership with Alexs Lemonade Stand Foundation (ALSF) continued, RUNX1 Familial Research Program granted $200,000 for research grants and $165,000 to Early Career Investigation (ECI) grants. Research grants were awarded to seven projects entitled Modeling Familial Platelet Disorder Mutations in Mice, Drug Screen for FPD/AML Therapeutics , Role of Inflammatory Microenvironment in Clonal Evolution and Progression from FPD to AML, Characterization of Pre-Leukemia Associated with Familial RUNX1 Mutations, Pharmacologic Enhancement of Residual Wild Type RUNX1 Protein Activity in RUNX1-FPD, and Identifying Therapeutic Targets to Prevent Progression of Familial RUNX1 Disorder to AML using Novel iPSC Models. Four early career investigators were supported. 487615 287750 2022 Independent grants include the continued support of researcher Dr. Nancy Speck at the University of Pennsylvania ($200,000) in the optimization of RUNX1-FPD CHIP mouse models. Other independent grants include projects that support an International RUNX1 database to aggregate clinicial and genetic patient data led by University of South Australia (87,750). 423644 250000 Sponsored Research. In Partnership with the National Institutes of Health, National Institute of Allergy and Infectious Disease (NIAID) and National Cancer Institute (NCI), this grant mechanism supports a total of 2 projects with scientific investigators at Boston Childrens Hospital and their collaborators at NIAID and NCI. The two projects are entitled, Rescue of RUNX1 deficiency phenotypes in RUNX1-FPD patients treated with imatini and Defining clonal and metabolic alterations in the evolution of RUNX1-FPD. 338915 200000 Sponsored Research. 2022 Focused Impact Research (FIRE) grant program. Continued co-funding partnership with EP Evans Foundation supported two projects aimed at determining the role of inflammation in the initiation and progression of hematologic malignancies driven by germline RUNX1 mutations. 762559 450000 2504161 true true false false false false false false false false false false false false true true true false false false true true false false false false false true false true false false false false false false false false false false false false false false false false false true 11 0 true 6 true false false false false false false false false false false false false X 3 3 true false false false false false false true true false false false false false false false false false CA X The Organization 8058804105 1482 E Valley Rd Ste 137 Santa Barbara CA 93108 Katrin Ericson President Executive Directo 40.00 0.00 X X 408485 0 20500 Monica Babich Secretary Treasurer CFO 15.00 0.00 X X 0 0 0 Timothy Babich Chairperson 15.00 0.00 X X 0 0 0 408485 0 20500 1 false true false 56145 614574 670719 670719 0 0 0 1340000 1340000 137750 137750 408485 347212 40849 20424 365871 231267 134604 48768 36432 2573 9763 61660 46063 3253 12344 44872 33521 2367 8984 14192 14192 44407 44407 100000 55363 44637 12401 12401 30163 25636 1811 2716 4870 4870 55161 41208 2910 11043 11784 8803 622 2359 136399 136399 4012 4012 Program Research 59637 59637 2880432 2504161 161633 214638 3051996 771163 28852 32000 4218 4218 3085066 807381 43495 33847 206145 147821 249640 181668 X 2835426 625713 2835426 625713 3085066 807381 -2209713 0 X false true X true false X 1543801 2366353 1431309 5335888 670719 11348070 1543801 2366353 1431309 5335888 670719 11348070 7277317 4070753 961 671 201 1833 11349903 0.35870 X RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED EIDL Note Payable 147821 147821 X 670719 670719 670719 2880432 2880432 2880432 Footnote for uncertain tax position under FIN 48 (Part X) The Organization has adopted the Financial Accounting Standards Board (FASB) Accounting Standards Codification (ASC) FASB ASC 740-10, Income Taxes, which prescribes measurement and disclosure requirements for current and deferred income tax provisions. The interpretation provides for a consistent approach in identifying and reporting uncertain tax provisions. It is managements belief that the Organization does not hold any uncertain tax positions. true East Asia and the Pacific Program services Research 87500 Europe including Iceland and Greenland Program services Research 50000 137500 137500 East Asia and the Pacific Independent Research 87500 Europe including Iceland and Greenland Research partnered with ALSF 50000 false false false false false false true BOSTON CHILDRENS HOSPITAL 300 LONGWOOD AVE Boston MA 02115 042774441 501c3 250000 Research partnered with NIH Boston Childrens Hospital 300 Longwood Ave Boston MA 02115 042864081 501c3 80000 Research in partnership with ALSF CHILDRENS HOSPITAL OF PHILADELPHIA 3615 CIVIC CENTER Philadelphia PA 19101 232237932 501c3 50000 Research partnered with ALSF DANA FARBER CANCER INSTITUTE 450 BROOKLINE AVE Boston MA 02215 042263030 501c3 45000 Research partnered with ALSF Albert Einstein College of Medicine 1300 Morris Park Ave Bronx NY 10461 830621846 501c3 30000 Research partnered with ALSF LELAND STANFORD JUNIOR UNIVERSITY 215 PANAMA STREET BUILDING D Stanford CA 94305 941156365 501c3 125000 Research partnered with MFCR MEMORIAL SLOAN KETTERING CANCER CTR 1275 YORK AVENUE New York NY 10065 131624082 501c3 30000 Research in partnership with ALSF OREGON HEALTH & SCIENCE UNIV FOUNDA 1121 SW SALMON STREET SUITE 100 Portland OR 97205 237083114 501c3 150000 Research pship with ALSFEP Evans UNIVERSITY OF MASSACHUSETTS MEDICAL 55 LAKE AVENUE Worcester MA 01655 043108190 501c3 125000 Research partnered with MFCR UNIVERSITY OF PENNSYLVANIA 338 SOUTH 19TH STREET Philadelphia PA 19103 231352685 501c3 200000 Independent Research UNIVERSITY OF CHICAGO 5841 S MARYLAND AVE Chicago IL 60637 363488183 501c3 125000 Research in partnership with MFCR Vanderbilt University School of Med 1161 21st Ave S D3300 Nashville TN 37232 621816811 501c3 100000 Research pship with EP Evans Univ of Washington School of Medici 1959 NE Pacific S Seattle WA 98195 431519670 501c3 30000 Research partnered with ALSF X X false false false false false false false false false Katrin Ericson President Executive Director 292722 115763 20500 428985 Officer directors etc family relationship Part VI line 2 Timothy and Monica Babich, the two co-directors, are married. Form 990 governing body review Part VI line 11 The Voting Members of the Organization have reviewed the form 990 and all schedules and have unanimously agreed on its accuracy. All members have received a copy for their records. Governing documents etc available to public Part VI line 19 The Organization will publish financial information, governing documents and conflict of interest policy on the Organizations website. Part III response or note to any other line in Part III Part I - Summary and Part III - Organizations Mission StatementTo provide grants for relevant research projects to find a cure for RUNX1-FPD, to raise public awareness, and to strengthen the community by providing a forum to help connect, inform and educate RUNX1-FPD patients and their families.