2023-04-18T09:14:49-00:00 2022-12-31 990 2022-01-01 843289802 ALS CURE PROJECT INC % Barron Wesenberg ALSC 9253215487 2808 LONGSPUR WAY Pleasanton CA 945665206 Barron Wesenberg Treasurer 9253215487 2023-04-18 false Barron Wesenberg XXX-XX-XXXX true 3 AAL1 IAL1 2022 2023-04-26 12:10:37Z Mike Piscotty 2808 Longspur Way Pleasanton CA 94566 474477 false X alscure.net X 2019 CA The specfic purpose of the Organization shall include without limitation, to lead scientific research focused on the identification of Amyotrophic Lateral Scierosis ALS bio-markers and disease mechanism 8 8 0 20 0 404785 143790 0 0 14554 404785 158344 225000 240000 0 0 0 4028 7019 5563 232019 245563 172766 -87219 265376 178157 0 265376 178157 X This year the ALS Cure Project has funded multi-gene modeling at Stanford University and Sheffield University as funding research utilizing Sierram, the Lawerence Livermore Natonal Lab supercomputer, in multi-modal longitudinal modeling and physics-based modeling of TDP-43 protein aggregates which are present in over 95 of ALS cases. false false 90000 ALS Cure Project continued to fund the Physics based modeling project using the worlds fastest supercomputer at Lawerance Livermore Lab to help idenity and understand the ALS disease mechanism. The initial focus will be on the formation of the aberrant TAR DNA- binding protien 43 TDP-43 inclusions or cluster that transition into pathological, amyyloid-like fibrils 100000 ALS Cure Project funded a pilot program to evaluate the applicability of LLNLs Brain-on-chip platform to support an in vitro ALS model recapitulating key disease phenotype. This capability can then be used to probe neuronal function as a readout of efficacy to therapeutic compounds, including those being developed at Prosetta Biosciences. 50000 The ALS Cure Project seeded 2 research project Barrow Neuro and Triparite selected from the ALS Innovation Symposim held virtual on November 17th and December 1stof 2021 that included 115 international ALS researchers from 10 nations where participants worked collaboratively in workshop styled breakouts to create the symposiums product. The event was also co-sponsored by Mitsubishi Tanabe Pharma America MTPA 240000 true true false false false false false false false false false false false false false false false false false false false false false false true false false true false false false false false false false false false false false false false false false false false false false true 0 0 0 false false false false false false false false false false false false X 8 8 true false false false false false false true false false false true true true true false false false false false CA X X X Barron Wesenberg 9253215487 2808 Longspur Pleasanton CA 94566 X Mike Piscotty President 010.00 X X 0 0 0 Stephen Piscotty VIce President 001.00 X 0 0 0 Toni Eslick Secretary 006.00 X 0 0 0 James Gilbreth Fund Raising Director 006.00 X 0 0 0 Barron Wesenberg Treasurer 003.00 X 0 0 0 Andrew Woodward IT Communications Director 003.00 X 0 0 0 Phil Green Corporate Sponsorship Director 003.00 X 0 0 0 Jim Poole Strategic Partnership Director 003.00 X 0 0 0 false false false 143790 143790 330687 143790 316133 14554 158344 240000 240000 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 1486 1486 2542 2542 0 0 0 0 0 0 0 0 1535 1535 0 245563 240000 1535 4028 233276 178157 32100 265376 178157 0 0 X 265376 133157 45000 265376 178157 265376 178157 -87219 X false false false X 523773 404785 143790 1072348 523773 404785 143790 1072348 1072348 0 0 0 0 523773 404785 143790 1072348 X 0.00000 0.00000 RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED RESTRICTED X false Top Golf 49092 16903 32189 23715 8474 Country Fest 153039 1759 151280 20758 39114 64683 26725 3 128556 26196 102360 63069 28793 5000 35802 330687 44858 285829 107542 76381 69683 62527 316133 -30304 true Livermore Lab Foundation 1111 Franklin St Oakland CA 94607 812567763 60000 Research fro Bio Markers Stanford University 450 Serra Mall Stanford CA 94035 941156365 155000 Multimodal analysis Barrow Neurological Foundation 2910 N 3rd Ave Suite 450 Phoenix AZ 85013 860174371 25000 Neuro Research 3 Part I Line 2 All progress/results are monitored by the research council,. Funds are staggered and timed to release as activities occur Form 990, Part I, Line 1 The Specfic purpose of the Organization shall include without limitation, to lead scientific research on the indentification of Amyotrophic Lateral Scierssis ALS bio-markers and diease mechanism with the ultimate goal of finding a cure for ALS Form 990, Part III, Line 2 ALS Cure Project has funded Physics based modeling project using the worlds fastest supercomputer at Laverance Livermore Labs to help identify and ndersatnd the ALS disease mechanism. Addtionally we are funding Vitro Drug research, Multi-modal and 3D functional modeling, a Tripartite research and working with the Barrow Neurological foundation Form 990, Part VI, Section A, Line 8b Meeting minutes are taken at each meeting and distributed to all members for review Form 990, Part VI, Section B, Line 11b A full and unredacted copy of this form 990 including schedules will be provided to all board memebers via email for review before filing Form 990, Part VI, Section B, Line 12c Pursuant to the organizations Conflict of Interest Policy, all Board Members and Officers are required at minimum to confirm or report in writing the existence/absence of any conflicts of interest at the annual meeting. Also, Board members and Officers are required to inform the board, in writing, that a conflict of interest has arisen at any time during the year as well. Form 990, Part VI, Section C, Line 19 The organizations website alscure.net provides te email address of the President for inquiries from the general public and the organizations has a profile on guidestar.org that provides the tax documents of the organization Form 990, Part VI, Section A, Line 2 Mike Piscotty Family relationship to Stephen Piscotty Barron Wesenberg busines relationship to James Gilbreth.